DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4766 and Mab21l1

DIOPT Version :9

Sequence 1:	NP_572287.1	Gene:	CG4766 / 31533	FlyBaseID:	FBgn0027546	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001102967.1	Gene:	Mab21l1 / 688394	RGDID:	1589984	Length:	359	Species:	Rattus norvegicus

Alignment Length:	362	Identity:	263/362 - (72%)
Similarity:	307/362 - (84%)	Gaps:	3/362 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MMAAQTRMVYQMNRFCTERVQARMYKTATAIREICKIVQDILKEVELQEPRFISSLVECNGRFEG 71
            |:|||.::||.:|::..|:.|||....|..|||:||:|.|:|||||:|||||||||.|.:.|:||
  Rat     1 MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEG 65

  Fly    72 VEVISPNEFEIVLYLNQMGVFNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSSRKIRA 136
            :|||||.|||:||||||||||||||||:|||||||||||||||||||||||||||||||:||||:
  Rat    66 LEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRS 130

  Fly   137 RFQTLVAQACDKSVYRDMVKMVGDTSEVKLRIRERFVVQITPAFKCSGIWPRSAAHWPVPHLPWP 201
            |||||||||.||..|||:||||.||||||||||:|:||||||||||:|||||||||||:||:|||
  Rat   131 RFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWP 195

  Fly   202 HPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSFFEAENRLLQGGCRRRCLSMLKTL 266
            .||.|||||.|||:|||||...:..|.::|   |.|||||.|.||||||..||||::|||:||||
  Rat   196 GPNRVAEVKAEGFNLLSKECHSLAGKQSSA---ESDAWVLQFAEAENRLQMGGCRKKCLSILKTL 257

  Fly   267 RDRHLDLPGNPISAYHLKNLLLYECEKHPRDFEWDEGCIADRINGIFLQLISCLQYRRCPHYFLP 331
            |||||:|||.|::.||:|.|:.||||||||:.:|||.|:.||:|||.||||||||.|||||||||
  Rat   258 RDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLP 322

  Fly   332 ALDMFKGKSPSALEQAAKQVWRLTRELLTNANAFEKL 368
            .||:|:||..||||.||||.|||.||:|||..:.|||
  Rat   323 NLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4766	NP_572287.1	Mab-21	68..353	CDD:281298	218/284 (77%)
Mab21l1	NP_001102967.1	Mab-21	62..344	CDD:397398	218/284 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351178
Domainoid	1	1.000	482	1.000	Domainoid score	I390
eggNOG	1	0.900	-	-		E1_KOG3963
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	579	1.000	Inparanoid score	I990
OMA	1	1.010	-	-		QHG48626
OrthoDB	1	1.010	-	-		D336176at33208
OrthoFinder	1	1.000	-	-		FOG0002743
OrthoInspector	1	1.000	-	-		mtm9046
orthoMCL	1	0.900	-	-		OOG6_105865
Panther	1	1.100	-	-	LDO	PTHR10656
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1828
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770