DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4766 and Cgas

DIOPT Version :9

Sequence 1:	NP_572287.1	Gene:	CG4766 / 31533	FlyBaseID:	FBgn0027546	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_038938458.1	Gene:	Cgas / 682147	RGDID:	1586939	Length:	510	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	82/372 - (22%)
Similarity:	154/372 - (41%)	Gaps:	84/372 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ERVQARMYKTATAIREICKIVQDILKEVELQEPRF--ISSLVECNGRFEGVEVISPNEFEIVLYL 86
            ::::.:..:.:.|...:.|:|..:|:.::.:|..|  :..| .....:|.|::.:||||:::..|
  Rat   158 DKLRLKRKEISAAAETVNKVVDQLLRRMQRRESEFKGVEQL-NTGSYYEHVKISAPNEFDVMFKL 221

  Fly    87 N----------QMGVFNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSSRKIRARFQTL 141
            .          :.|.|..|....:|          |...:|.::|    ...||:.|:.::|:.|
  Rat   222 EVPRIELEEYYETGAFYRVKFKRIP----------RGNPLSHFLE----GEVLSATKVLSKFREL 272

  Fly   142 VAQACDKSVYRDMVKMVGDTS-----------EVKLRIR--ERFVVQITPAFKCSGIWPRSAAHW 193
            :         ::.||.:.||.           .|.|.||  |...|.|..|.:..|.||.| ...
  Rat   273 I---------KEEVKEIKDTDVTVEEEKPGSPAVTLLIRNPEEISVDIILALESKGSWPIS-TKG 327

  Fly   194 PVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSFFEAENRLLQGG---- 254
            .:|...|....:...::.|.|.|:.|.:     |:.|  ..:|:.|.|||...|..:|...
  Rat   328 GLPIQDWLGTKVRTNLRREPFYLVPKNA-----KDGN--RFQGETWRLSFSHTEKYILNNHGIGK 385

  Fly   255 ----------CRRRCLSMLKTLRD------RHLDLPGNPISAYHLKNLLLYECEKHPRDFEWDEG 303
                      ||:.||.::|.|.:      :.||    ...:||:|..:.:...|.|:|.:||..
  Rat   386 TCCESSGAKCCRKECLKLMKYLLEQLKREFQELD----AFCSYHVKTAIFHMWTKDPQDSQWDPR 446

  Fly   304 CIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAAKQ 350
            .::...:......:.||:..:..|||:|..::|   |...:::.:|:
  Rat   447 NLSTCFDKFLTFFLECLRTEKLDHYFIPKFNLF---SQELIDKKSKE 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4766	NP_572287.1	Mab-21	68..353	CDD:281298	75/326 (23%)
Cgas	XP_038938458.1	PHA03247	<2..143	CDD:223021
Cgas	XP_038938458.1	Mab-21	203..498	CDD:397398	75/326 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910