DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4766 and Tmem102

DIOPT Version :9

Sequence 1:	NP_572287.1	Gene:	CG4766 / 31533	FlyBaseID:	FBgn0027546	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001028605.2	Gene:	Tmem102 / 380705	MGIID:	1921591	Length:	509	Species:	Mus musculus

Alignment Length:	218	Identity:	52/218 - (23%)
Similarity:	77/218 - (35%)	Gaps:	51/218 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 RERFVVQITPAFKCSGIWPRSA-AHWPVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAA 232
            |...:..:.|....:| ||.:| :|      .|..| :|:|         |....::........
Mouse   312 RHLLLFDLIPVVTVTG-WPDTARSH------SWAGP-LVSE---------SASFYLVPGSLPEQP 359

  Fly   233 SMEGDAWVLSFFEAE--------NRLLQGGCRRRCLSMLKTLRDRHLDLPGNPISA-YHLKNLLL 288
            |..|  |.|.|...|        ..|||.....:.|  |:.|      :.|...:| |.|:.||.
Mouse   360 STSG--WQLCFARQELALKERIPTPLLQAHAAAQAL--LRPL------VAGTRAAAPYLLRTLLY 414

  Fly   289 YECEKHP-----RDFEWDEGCIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAA 348
            :.||:.|     |.......|:     |:..:|...|:....|||||....:..|...:||..|.
Mouse   415 WACERLPALYLARPENAGACCL-----GLLDELSRVLEAGALPHYFLSGRKLRVGDGSAALRGAL 474

  Fly   349 KQV----WRLTRELLTNANAFEK 367
            .|:    .:..||.:..|....|
Mouse   475 AQLRGDPAQALREAVEEAKVARK 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4766	NP_572287.1	Mab-21	68..353	CDD:281298	48/202 (24%)
Tmem102	NP_001028605.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..236
Tmem102	NP_001028605.2	Mab-21	<318..456	CDD:281298	40/169 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3963
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10656
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910