Protein Alignment CG5966 and PNLIPRP1

DIOPT Version :10

• Sequence 1: NP_572286.1
• Gene: CG5966 / 31532
• FlyBaseID: FBgn0029831
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_006220.1
• Gene: PNLIPRP1 / 5407
• HGNCID: 9156
• Length: 467
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 156/499 - (31%)
• Similarity: 241/499 - (48%)
• Gaps: 73/499 - (14%)

  Fly    46 CFGVYGCFPINGPW-NTVTRSINVHPQKPSEIEPHFTLHTRRALDQPKYLDLNDPESVQGMGMNP 109
            |:...|||....|| .|..|.:.:.|..|.:|...|.|:|....:..:.|.|:||.:::......
Human    21 CYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQM 85

  Fly   110 KGKIFLLVHGYLESGEIPWMWDMAKALLAHEPEGRASVVLIDWGGGASPPYVQAVANIRLVGAIT 174
            ..|...::||:::.|:..|:.||.|.|...|   ..:.:.:||..|:...|.||..|:|:|||..
Human    86 DRKTRFIIHGFIDKGDESWVTDMCKKLFEVE---EVNCICVDWKKGSQATYTQAANNVRVVGAQV 147

  Fly   175 AHVVHMLYEELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAPLFTDTDPI 239
            |.::.:|..|...|. ..||:||||||||::|.||....   ||  :|||||||....|..|...
Human   148 AQMLDILLTEYSYPP-SKVHLIGHSLGAHVAGEAGSKTP---GL--SRITGLDPVEASFESTPEE 206

  Fly   240 VRLDKTDAHFVDIVHTDANPLMKG-GLGINMRLGHVDFFPNGGFDNPGCNKK-FQDVVKKKTLFL 302
            ||||.:||.|||::||||.||:.. |.|.|.::||:|||||||...|||.|. ...:|....::.
Human   207 VRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWA 271

  Fly   303 TMQEFLGCNHIRSQQYFTESIGSQCPFLGITCDSFESFKDTKCTSCEEPGHTCLRMGYH------ 361
            ..::|:.|||:||.:|:.|||.:...|....|.|::||:..||..|.:.|  |.:||::
Human   272 GTRDFVACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESDKCFPCPDQG--CPQMGHYADKFAG 334

  Fly   362 -SQEDYQEQVDLGQLQQGDSPGVFYLWTGDSKPFCRLHYRITVRVSGHDESTLHGGEVGILSIQL 425
             :.|:.|:               |:|.||::..|.|..|.:::.:||.   |..|        |:
Human   335 RTSEEQQK---------------FFLNTGEASNFARWRYGVSITLSGR---TATG--------QI 373

  Fly   426 HDALVKKAGKNERAATEMMKFSQKAMYFEPG----YEYKALVAGRNLREPEYATVNWEYPTNILN 486
            ..||....|...       ::|......:||    ||:.|.:....:.:.::.   |.  .|::|
Human   374 KVALFGNKGNTH-------QYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFL---WN--NNVIN 426

  Fly   487 PLTWRILSAPRIYLEYILIEAMESSDLYLKLCPQ---HEGAILT 527
            |      :.|::....|.::..|...:| ..|.:   .|..:||
Human   427 P------TLPKVGATKITVQKGEEKTVY-NFCSEDTVREDTLLT 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	116/322 (36%)
PNLIPRP1	NP_006220.1	Lipase	18..353	CDD:395099	127/357 (36%)
		PLAT_PL	356..467	CDD:238857	27/138 (20%)