DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5966 and lipca

DIOPT Version :9

Sequence 1:	NP_572286.1	Gene:	CG5966 / 31532	FlyBaseID:	FBgn0029831	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	351	Identity:	109/351 - (31%)
Similarity:	161/351 - (45%)	Gaps:	42/351 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LDLNDPESVQGMGMNPKGKIFLLVHGYLESGEI-PWMWDMAKALLAHEPEGRASVVLIDWGGGAS 157
            |:|..|.::...|.|....:.:::||:...|.: .|:..:|.||  ...||..:|::.||...|.
Zfish    61 LELFQPHTLDACGFNSSLPLAIIIHGWSVDGMMEKWISRLASAL--KSSEGNINVLIADWLTLAH 123

  Fly   158 PPYVQAVANIRLVGAITAHVVHMLYEELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPAR 222
            ..|..|..|.|:||...||::..|.:..:.| |..||:||:|||||:||:||.:|... |....|
Zfish   124 QHYPIAAQNTRIVGQDIAHLLSWLEDFKQFP-LGKVHLIGYSLGAHISGFAGSNLAMS-GRTLGR 186

  Fly   223 ITGLDPAAPLFTDTDPIVRLDKTDAHFVDIVHTDANPLMKGGLGINMRLGHVDFFPNGGFDNPGC 287
            |||||||.|:|.......||...||.|||.:||.....|...:||...:.|.||:||||...|||
Zfish   187 ITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVGIKQPVAHFDFYPNGGSFQPGC 251

  Fly   288 NKKFQDVVKKKTL--FLTMQEFLGCNHIRSQQYFTES-IGSQCPFLGITCDSFESFKDTKCTSCE 349
            ....|::......  .:..::.:.|.|.|:...|.:| :......:...|....:|....|..|.
Zfish   252 QLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDKQIMAYKCSDNTAFDKGNCLDCR 316

  Fly   350 EPGHTCLRMGYHSQEDYQEQVDLGQLQQGDSPGVFYLWTGDSKPFCRLHYR-------------- 400
            :  :.|..:||          |:.:::.|.|..:| |.|....|:...||:
Zfish   317 K--NRCNTLGY----------DIKKVRTGKSKRLF-LKTRSHMPYKLFHYQFRIQFINQIDKIDP 368

  Fly   401 -ITVRVSGHDESTLHGGEVGILSIQL 425
             :||.:||    ||  ||...|.|.|
Zfish   369 TLTVSLSG----TL--GESENLPITL 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Lipase	46..394	CDD:278576	95/303 (31%)
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	95/299 (32%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	109/351 (31%)
		Pancreat_lipase_like	54..344	CDD:238363	95/299 (32%)
		PLAT_LPL	351..485	CDD:238856	13/44 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I4202
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.970