Protein Alignment CG5966 and PNLIPRP3

DIOPT Version :9

• Sequence 1: NP_572286.1
• Gene: CG5966 / 31532
• FlyBaseID: FBgn0029831
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001011709.2
• Gene: PNLIPRP3 / 119548
• HGNCID: 23492
• Length: 467
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 140/432 - (32%)
• Similarity: 212/432 - (49%)
• Gaps: 62/432 - (14%)

  Fly    46 CFGVYGCFPINGPWNTVTRSINVH----PQKPSEIEPHFTLHTRRALDQPK-YLDLN--DPESVQ 103
            |:...|||....||   ||:.:..    |..|.:|...|.|:|   :..|. |.:::  :..::|
Human    21 CYERLGCFKDGLPW---TRTFSTELVGLPWSPEKINTRFLLYT---IHNPNAYQEISAVNSSTIQ 79

  Fly   104 GMGMNPKGKIFLLVHGYLESGEIPWMWDMAKALLAHEPEGRASVVLIDWGGGASPPYVQAVANIR 168
            ...........:.:.|:...|:  |..||...||..|.   .:.:.:||..| |..|:.||.|:|
Human    80 ASYFGTDKITRINIAGWKTDGK--WQRDMCNVLLQLED---INCINLDWING-SREYIHAVNNLR 138

  Fly   169 LVGAITAHVVHMLYEELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAPLF 233
            :|||..|:.:.:|.::... :...||:|||||||||:|.||..:.   ||  .||||||||.|.|
Human   139 VVGAEVAYFIDVLMKKFEY-SPSKVHLIGHSLGAHLAGEAGSRIP---GL--GRITGLDPAGPFF 197

  Fly   234 TDTDPIVRLDKTDAHFVDIVHTD-ANPLMKGGLGINMRLGHVDFFPNGGFDNPGCNK------KF 291
            .:|...||||.:||:|||::||: |..|.:.|:|.....||:||:||||...|||..      ||
Human   198 HNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACGHLDFYPNGGKHMPGCEDLITPLLKF 262

  Fly   292 QDVVKKKTLFLTMQEFLGCNHIRSQQYFTESIGSQCPFLGITCDSFESFKDTKCTSCEEPGHTCL 356
            .....||    .|..|..|||.||.|::.|||.:...|:...|.|:.|||...|..|.:.|  |.
Human   263 NFNAYKK----EMASFFDCNHARSYQFYAESILNPDAFIAYPCRSYTSFKAGNCFFCSKEG--CP 321

  Fly   357 RMGYHSQEDYQEQVDLGQLQQGDSPGVFYLWTGDSKPFCRLHYRITVRVSGHDESTLHGGEVGIL 421
            .||:     :.::.....::...|.  ::|.||...||.|..::::|::||.:.:.      |.:
Human   322 TMGH-----FADRFHFKNMKTNGSH--YFLNTGSLSPFARWRHKLSVKLSGSEVTQ------GTV 373

  Fly   422 SIQLHDALVKKAGKNERAATEMMKFSQKAMYFEPGYEYKALV 463
            .:::..| |:|.|          :|:..:...|||..|..|:
Human   374 FLRVGGA-VRKTG----------EFAIVSGKLEPGMTYTKLI 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Lipase	46..394	CDD:278576	123/361 (34%)
		Pancreat_lipase_like	76..390	CDD:238363	112/323 (35%)
PNLIPRP3	NP_001011709.2	Lipase	18..352	CDD:278576	123/361 (34%)
		Pancreat_lipase_like	52..348	CDD:238363	112/323 (35%)
		PLAT_PL	355..467	CDD:238857	14/67 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	228	1.000	Domainoid score	I2491
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3369
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	1	1.000	-	-		FOG0001245
OrthoInspector	1	1.000	-	-		otm41219
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X699
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.930