DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5966 and lipg

DIOPT Version :9

Sequence 1:	NP_572286.1	Gene:	CG5966 / 31532	FlyBaseID:	FBgn0029831	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002934486.2	Gene:	lipg / 100498513	XenbaseID:	XB-GENE-1011639	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	394	Identity:	115/394 - (29%)
Similarity:	177/394 - (44%)	Gaps:	67/394 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 EIEPH--FTLHTRRALDQPKYLDLNDPESVQGMGMNPKGKIFLLVHGYLESGEI-PWMWDMAKAL 136
            ::.||  |.:|..: .|...:|.....|.:.....|...|.|:::||:..||.. .|:..:..||
Frog    48 DMNPHVRFNVHFSK-YDSGCFLIPGQEECLGNCNYNTSAKTFIVIHGWSMSGLFETWLHRLVGAL 111

  Fly   137 LAHEPEGRASVVLIDWGGGASPPYVQAVANIRLVGAITAHVVHMLYEELRLPNLDNVHIIGHSLG 201
              .|.|..|:|:::||...|...|..||.|..:||...|.::..|.|:..| :|:|||:||:|||
Frog   112 --QERERYANVIVVDWMNLAHQLYPDAVNNTMVVGKDIAVLMDWLQEKANL-SLENVHLIGYSLG 173

  Fly   202 AHLSGYAGYHLQHDFGLKPARITGLDPAAPLFTDTDPIVRLDKTDAHFVDIVHTDANPLMKGGLG 266
            ||::||||..:....|    ||||||||.|:|...:...||...||.|||::||.....:...:|
Frog   174 AHVAGYAGNFVTGRIG----RITGLDPAGPMFEGAEAHKRLSPDDADFVDVLHTYTREALGVSIG 234

  Fly   267 INMRLGHVDFFPNGGFDNPGCNKKFQDVVKKKTLFLTMQEFLGCNHIRSQQYFTES-IGSQCPFL 330
            |.|.:||:|.:||||...|||.  ..||: ....:.::.:.:.|.|.||...|.:| |.......
Frog   235 IQMPIGHIDIYPNGGDFQPGCG--LSDVL-GAIAYGSIGDAVKCEHERSVHLFVDSLIHKDQESF 296

  Fly   331 GITCDSFESFKDTKCTSCEEPGHTCLRMGYHSQEDYQEQVDLGQLQQGDSPGVFYLWTGDSKPFC 395
            ...|...:.||...|.||.:  :.|..:||:::.           .:.......:|.|....|:.
Frog   297 AFQCTDSDRFKKGICLSCRK--NRCNAIGYNAKR-----------MRSKRNSKMFLKTRAQMPYK 348

  Fly   396 RLHYRITVRVSGHDES---------TLHG-------------GEVG-----------------IL 421
            ..||::.:.:..:.::         ||.|             ||:|                 :|
Frog   349 VFHYQMKMHIFNYKDALESEPTFSVTLMGTLNDSAPLPLAVPGEIGYNYTNTFLVYTEENIGELL 413

  Fly   422 SIQL 425
            .|||
Frog   414 KIQL 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Lipase	46..394	CDD:278576	102/322 (32%)
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	102/317 (32%)
lipg	XP_002934486.2	lipo_lipase	63..488	CDD:132274	111/378 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110