DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5966 and LOC100486161

DIOPT Version :9

Sequence 1:	NP_572286.1	Gene:	CG5966 / 31532	FlyBaseID:	FBgn0029831	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_031761958.1	Gene:	LOC100486161 / 100486161	-ID:	-	Length:	467	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	154/471 - (32%)
Similarity:	232/471 - (49%)	Gaps:	65/471 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CFGVYGCFPINGPW-NTVTRSINVHPQKPSEIEPHFTLHTRRALDQPKYLDLNDPESVQGMGMNP 109
            |:...||||.:.|| .||.|.||..||.|.:|...|.|.|::..:..:.:...:|.|:.......
Frog    21 CYNRIGCFPDSVPWAGTVERPINHLPQSPEKINTRFLLFTQQNPNSYQEISAINPSSISSSYFRT 85

  Fly   110 KGKIFLLVHGYLESGEIPWMWDMAKALLAHEPEGRASVVLIDWGGGASPPYVQAVANIRLVGAIT 174
            ..|...::||:::.||..|:.||.|.:|..|.   .:.:.:||.||:...|.||..|||:|||..
Frog    86 NRKTRFIIHGFIDKGEESWLTDMCKTMLQVED---VNCLCVDWMGGSRTLYTQAANNIRVVGAEV 147

  Fly   175 AHVVHML-----YEELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAPLFT 234
            |:.:..|     |.    |.:  ||:|||||||..:|.||...:   |:  .||||||||.|.|.
Frog   148 AYFIDTLTNMYGYS----PAM--VHVIGHSLGAQAAGEAGKRRK---GI--GRITGLDPAEPYFQ 201

  Fly   235 DTDPIVRLDKTDAHFVDIVHTDANPLMKG-GLGINMRLGHVDFFPNGGFDNPGCNKK-FQDVVKK 297
            .|...||||.:||:|||::||||.|::.. |||::...||:|||||||.:.|||.|. ...:|..
Frog   202 GTPSEVRLDSSDANFVDVIHTDAAPMVPNLGLGMSQLAGHLDFFPNGGEEMPGCKKNALSQIVDL 266

  Fly   298 KTLFLTMQEFLGCNHIRSQQYFTESIGSQCPFLGITCDSFESFKDTKCTSCEEPGHTCLRMGYHS 362
            ..::...::|:.|||:||.:|:|.||..:..|:|....::::||......|  |...|..|| |.
Frog   267 DGIWQGTRDFVACNHLRSYKYYTNSILKRDGFVGFPSSTYDTFKTGAVFPC--PSGGCPLMG-HY 328

  Fly   363 QEDYQEQVDLGQLQQGDSPGVFYLWTGDSKPFCRLHYRITVR------VSGHDESTLHGGEVGIL 421
            .:.|..|:...|        .::|.|||.|.|.|..|::||:      |.|:....|:||.....
Frog   329 ADTYTGQIINSQ--------KYFLNTGDEKEFARWRYKVTVQIISSSDVQGYFNVALYGGNGNTR 385

  Fly   422 SIQLHDALVKKAG--------KNERAATEMMKF-----------------SQKAMYFEPGYEYKA 461
            ..:::...:|...        :::....:.:||                 |....|.:.|..|:.
Frog   386 QYEVYKGTLKSGSSHSAFIDVESDVGTLDKVKFVWNNNLINPLLPTVGAQSVTVQYGKDGRTYRF 450

  Fly   462 LVAGRNLREPEYATVN 477
            ..:| ::||....|:|
Frog   451 CGSG-SVREEVLQTLN 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Lipase	46..394	CDD:278576	132/355 (37%)
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	114/320 (36%)
LOC100486161	XP_031761958.1	Lipase	18..352	CDD:395099	132/355 (37%)
LOC100486161	XP_031761958.1	PLAT_PL	355..467	CDD:238857	20/112 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010