DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5966 and LOC100486017

DIOPT Version :9

Sequence 1:	NP_572286.1	Gene:	CG5966 / 31532	FlyBaseID:	FBgn0029831	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_031761957.1	Gene:	LOC100486017 / 100486017	-ID:	-	Length:	467	Species:	Xenopus tropicalis

Alignment Length:	509	Identity:	159/509 - (31%)
Similarity:	241/509 - (47%)	Gaps:	85/509 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GGLMLQTMLYLANHTSRAAVNTLVDLPPAPKSDINEVK----CFGVYGCFPINGPW-NTVTRSIN 67
            |||.|.|:|                        :..||    |:...||||.:.|| .||.|.||
Frog     3 GGLWLVTLL------------------------VGAVKGGEVCYNRIGCFPDSVPWAGTVERPIN 43

  Fly    68 VHPQKPSEIEPHFTLHTRRALDQPKYLDLNDPESVQGMGMNPKGKIFLLVHGYLESGEIPWMWDM 132
            ..||.|.:|...|.|.|::..:..:.:...:|.::.........|...::||:::.||..|:.||
Frog    44 HLPQSPEKINTRFLLFTQQNPNSYQEISAINPSTISASNFRSTRKTRFIIHGFIDKGEESWLTDM 108

  Fly   133 AKALLAHEPEGRASVVLIDWGGGASPPYVQAVANIRLVGAITAHVVHMLYEEL-RLPNLDNVHII 196
            .|.:|..|.   .:.:.:||.||:...|.||..|||:|||..|:.:..|.... ..|.:  ||:|
Frog   109 CKTMLQVED---VNCLCVDWMGGSRTLYTQAANNIRVVGAEVAYFIDTLTSMYGHSPAM--VHVI 168

  Fly   197 GHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAPLFTDTDPIVRLDKTDAHFVDIVHTDANPLM 261
            ||||||..:|.||...:   |:  .||||||||.|.|..|...||||.:||.|||::||||.|::
Frog   169 GHSLGAQAAGEAGKRRK---GI--GRITGLDPAEPYFQGTPIEVRLDPSDAKFVDVIHTDAAPML 228

  Fly   262 KG-GLGINMRLGHVDFFPNGGFDNPGCNKK-FQDVVKKKTLFLTMQEFLGCNHIRSQQYFTESIG 324
            .. |||::..:||:|||||||.:.|||.|. ...::....::...::|:.|||:||.:|:|.||.
Frog   229 PNLGLGMSQLVGHLDFFPNGGEEMPGCKKNALSQIIDIDGIWQGTRDFVACNHLRSYKYYTNSIL 293

  Fly   325 SQCPFLGITCDSFESFKDTKCTSCEEPGHTCLRMGYHSQEDYQEQVDLGQLQQGDSPGVFYLWTG 389
            .:..|:|....::::||......|  |...|..|| |..:.|..|:...|        .::|.||
Frog   294 KRDGFVGFPTATYDTFKSGAVFPC--PSGGCPLMG-HYADTYTGQIINSQ--------KYFLNTG 347

  Fly   390 DSKPFCRLHYRITVR------VSGHDESTLHGGEVGILSIQLHDALVKKAG--------KNERAA 440
            |.|.|.|..|::||:      |.|:....|:||.......:::...:|...        :::...
Frog   348 DEKEFARWRYKVTVQITSSRDVQGYFNVALYGGNGNTRQYEVYKGTLKSGSSHSAFIDVESDVGT 412

  Fly   441 TEMMKF-----------------SQKAMYFEPGYEYKALVAGRNLREPEYATVN 477
            .:.:||                 |....|.:.|..|:...:| ::||....|:|
Frog   413 LDKVKFVWNNNLINPLLPTVGAQSVTVQYGKDGRTYRFCGSG-SVREEVLQTLN 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Lipase	46..394	CDD:278576	129/351 (37%)
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	111/316 (35%)
LOC100486017	XP_031761957.1	Lipase	18..352	CDD:395099	129/354 (36%)
LOC100486017	XP_031761957.1	PLAT_PL	355..467	CDD:238857	20/112 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010