Protein Alignment CG6048 and PRSS22

DIOPT Version :10

• Sequence 1: NP_572282.1
• Gene: CG6048 / 31528
• FlyBaseID: FBgn0029827
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 91/290 - (31%)
• Similarity: 142/290 - (48%)
• Gaps: 48/290 - (16%)

  Fly    45 RIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPK 109
            |::.|.:::.......|.|:|.       ||.| |.|||:...||:||||||.|.:  :..::
Human   157 RVVGGEDSTDSEWPWIVSIQKN-------GTHH-CAGSLLTSRWVITAAHCFKDNL--NKPYL-- 209

  Fly   110 EEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDK----DIALLMLNGTVPTGHPTIRPI 170
              |.|::|   .:...|..:.:.:..:..::...:.::.:    ||||:.|..::.... .:.||
Human   210 --FSVLLG---AWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSE-RVLPI 268

  Fly   171 ALNRFAI--PEGVVCQVTGWGNTEDGYV---SDILMTVDVPMISEEHCINDSDLGHL-------- 222
            .|...:|  |....|.::|||:.:||..   ...|..:.||:|..|.|      .||
Human   269 CLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVC------SHLYWRGAGQG 327

  Fly   223 -IQPGMICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGIQCALPRLPGVYTEVSYYYD 282
             |...|:|||||| ||:|||.|||||||:||.:    |||::|||..||....||||..:|.:..
Human   328 PITEDMLCAGYLE-GERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRS 391

  Fly   283 WILQNMGENGEGSGEESGEGSGEGSGEGSG 312
            |: :.:.:..:..|...|.|:.....:|||
Human   392 WV-EKIVQGVQLRGRAQGGGALRAPSQGSG 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	84/260 (32%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	84/263 (32%)