DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6048 and KLK6

DIOPT Version :9

Sequence 1:NP_572282.1 Gene:CG6048 / 31528 FlyBaseID:FBgn0029827 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_001012982.1 Gene:KLK6 / 5653 HGNCID:6367 Length:244 Species:Homo sapiens


Alignment Length:221 Identity:83/221 - (37%)
Similarity:111/221 - (50%) Gaps:32/221 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 FGTGH-LCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMG--NLDRYNRTNTLTFTIEE 134
            :.:|| ||||.||.|.||||||||            .|....|.:|  || |...::....::..
Human    40 YTSGHLLCGGVLIHPLWVLTAAHC------------KKPNLQVFLGKHNL-RQRESSQEQSSVVR 91

  Fly   135 RIMQLDKFDLSTYDKDIALLMLNGTVPTGHPT-----IRPIALNRFAIPEGVVCQVTGWGNTEDG 194
            .::..| :|.:::|:||.||.|      ..|.     |:|:.|.|........|.:.|||.|.||
Human    92 AVIHPD-YDAASHDQDIMLLRL------ARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG 149

  Fly   195 YVSDILMTVDVPMISEEHCINDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSELAGVV 259
            ...|.:....:.::|.|.| ..:..|.:.| .|:|||..:.| ||:|.|||||||||...|.|:|
Human   150 DFPDTIQCAYIHLVSREEC-EHAYPGQITQ-NMLCAGDEKYG-KDSCQGDSGGPLVCGDHLRGLV 211

  Fly   260 SWG-IQCALPRLPGVYTEVSYYYDWI 284
            ||| |.|.....|||||.|..|.:||
Human   212 SWGNIPCGSKEKPGVYTNVCRYTNWI 237

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6048NP_572282.1 Tryp_SPc 45..284 CDD:214473 81/219 (37%)
KLK6NP_001012982.1 Tryp_SPc 23..237 CDD:214473 81/219 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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