Protein Alignment CG6048 and PRSS8

DIOPT Version :10

• Sequence 1: NP_572282.1
• Gene: CG6048 / 31528
• FlyBaseID: FBgn0029827
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 116/315 - (36%)
• Similarity: 151/315 - (47%)
• Gaps: 58/315 - (18%)

  Fly     1 MFGLGQLLAVALL----LIFLPSGLRGATTRTHLDTKAIRPRFNADPGRIINGTEASLGATRHQV 61
            :.|.|||.|||:|    |:...:|..||..          |...|...||..|:.|..|....||
Human     6 VLGPGQLGAVAILLYLGLLRSGTGAEGAEA----------PCGVAPQARITGGSSAVAGQWPWQV 60

  Fly    62 GIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMG--NLDRYN- 123
            .|.       :.|. |:|||||:...|||:|||||..:       ..||.:.|.:|  .||.|:
Human    61 SIT-------YEGV-HVCGGSLVSEQWVLSAAHCFPSE-------HHKEAYEVKLGAHQLDSYSE 110

  Fly   124 --RTNTLTFTIEERIMQLDKFDLSTYDKDIALLMLNGTVPTGHPTIRPIAL--NRFAIPEGVVCQ 184
              :.:||     :.|:....:.......|||||.|:..: |....||||.|  ...:.|.|:.|.
Human   111 DAKVSTL-----KDIIPHPSYLQEGSQGDIALLQLSRPI-TFSRYIRPICLPAANASFPNGLHCT 169

  Fly   185 VTGWGNTEDGYVSDI----LMTVDVPMISEE--HCINDSDL----GHLIQPGMICAGYLEVGEKD 239
            |||||:.... ||.:    |..::||:||.|  :|:.:.|.    .|.:|..|:||||:| |.||
Human   170 VTGWGHVAPS-VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVE-GGKD 232

  Fly   240 ACAGDSGGPLVCQSE----LAGVVSWGIQCALPRLPGVYTEVSYYYDWILQNMGE 290
            ||.|||||||.|..|    |.|:||||..|.....|||||..|.|..||...:.|
Human   233 ACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	99/259 (38%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	100/261 (38%)