DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_056590.2	Gene:	Tmprss2 / 50528	MGIID:	1354381	Length:	490	Species:	Mus musculus

Alignment Length:	266	Identity:	91/266 - (34%)
Similarity:	125/266 - (46%)	Gaps:	48/266 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQII---YDGTF 106
            ||:.|..||.|....||.:       :..|. |:||||:|.|.|::|||||..:.:.   |...|
Mouse   253 RIVGGLNASPGDWPWQVSL-------HVQGV-HVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAF 309

  Fly   107 VPKEEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDKDIALLMLNGTVPTGHPTIRPIA 171
            ..     ::..:|..|...:.:     |:::....:|..|.:.||||:.|.          .|:|
Mouse   310 AG-----ILRQSLMFYGSRHQV-----EKVISHPNYDSKTKNNDIALMKLQ----------TPLA 354

  Fly   172 LNRFAIP-----EGVV------CQVTGWGNT-EDGYVSDILMTVDVPMISEEHCINDSDLGHLIQ 224
            .|....|     .|::      |.::|||.| |.|..||:|....||:|....|.:.....:||.
Mouse   355 FNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLIT 419

  Fly   225 PGMICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGIQCALPRLPGVYTEVSYYYDWIL 285
            |.|||||:|: |..|:|.||||||||....    |.|..|||..||....||||..|:.:.|||.
Mouse   420 PAMICAGFLQ-GSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIY 483

  Fly   286 QNMGEN 291
            |.|..|
Mouse   484 QQMRAN 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	86/257 (33%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:373897
		Tryp_SPc	254..485	CDD:238113	87/259 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910