DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and prss27

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	283	Identity:	101/283 - (35%)
Similarity:	135/283 - (47%)	Gaps:	52/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 THLDTKAIRPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTA 92
            |.:.|...:|.|:   .||:.|..|..|....||.|        .:...|:|||||:...||::|
Frog   405 TAISTGCGQPAFS---DRIVGGNNAVFGEWPWQVSI--------VYQNSHICGGSLVSSNWVVSA 458

  Fly    93 AHCFVDQIIYDGTFVPK----EEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDKDIAL 153
            ||||           |:    |...|::|.....|.|:.......:|::....:.......|||:
Frog   459 AHCF-----------PRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAM 512

  Fly   154 LMLNGTVPTGHPTIRPIA--LNRFAIPEGVVCQVTGWGNTEDGYVSDI-------LMTVDVPMIS 209
            :.:...| |....|.||.  |.....|.|.:|.||||||.:    ||:       |..|:||:::
Frog   513 VEMESPV-TYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQ----SDVSLSPPYPLQEVEVPLVN 572

  Fly   210 EEHCIN----DSDLG---HLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGI 263
            ...|..    :|||.   .|:...||||||.| |:||||.|||||||.|:|.    |.|:||||.
Frog   573 ASSCDTMYHYNSDLNPATQLVHDDMICAGYPE-GQKDACQGDSGGPLACKSGNYWFLTGIVSWGD 636

  Fly   264 QCALPRLPGVYTEVSYYYDWILQ 286
            .||.|..|||||:||.:..||.|
Frog   637 GCAQPNRPGVYTKVSSFSSWINQ 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	94/262 (36%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	95/263 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910