Protein Alignment CG6048 and KLK12

DIOPT Version :9

• Sequence 1: NP_572282.1
• Gene: CG6048 / 31528
• FlyBaseID: FBgn0029827
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 91/296 - (30%)
• Similarity: 123/296 - (41%)
• Gaps: 90/296 - (30%)

  Fly     8 LAVALLLIFLPSGLRGATTRTHLDTKAIRPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYF 72
            |::.|||..|  ||..|.|                 .:|.||||....:...|||:        |
Human     3 LSIFLLLCVL--GLSQAAT-----------------PKIFNGTECGRNSQPWQVGL--------F 40

  Fly    73 FGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTLTFTIEERIM 137
            .||...|||.||...||||||||       .|:     .:.|.:|               |..:.
Human    41 EGTSLRCGGVLIDHRWVLTAAHC-------SGS-----RYWVRLG---------------EHSLS 78

  Fly   138 QLD--------KFDL---------STYDKDIALLMLNGTVPTGHPTIRPIALNRFAIPEGVVCQV 185
            |||        .|.:         ::::.|:.||.|...|.. ..:::|:.|.......|..|.|
Human    79 QLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV-TSSVQPLPLPNDCATAGTECHV 142

  Fly   186 TGWG--NTEDGYVSDILMTVDVPMISEEHCINDSDLGHLIQPG-----MICAGYLEVGEKDACAG 243
            :|||  |.......|:|..:::.::|...|       |.:.||     |:|||  .|..:|||.|
Human   143 SGWGITNHPRNPFPDLLQCLNLSIVSHATC-------HGVYPGRITSNMVCAG--GVPGQDACQG 198

  Fly   244 DSGGPLVCQSELAGVVSWGI--QCALPRLPGVYTEV 277
            ||||||||...|.|:||||.  .|....:|||||.:
Human   199 DSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	82/259 (32%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	82/259 (32%)
		Tryp_SPc	22..236	CDD:238113	82/258 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGUI
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810