DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6048 and KLK2

DIOPT Version :9

Sequence 1:NP_572282.1 Gene:CG6048 / 31528 FlyBaseID:FBgn0029827 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_005542.1 Gene:KLK2 / 3817 HGNCID:6363 Length:261 Species:Homo sapiens


Alignment Length:273 Identity:87/273 - (31%)
Similarity:119/273 - (43%) Gaps:62/273 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 RIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPK 109
            ||:.|.|....:...||.:       |..|..| |||.|:.|.||||||||.            |
Human    24 RIVGGWECEKHSQPWQVAV-------YSHGWAH-CGGVLVHPQWVLTAAHCL------------K 68

  Fly   110 EEFIVVMGNLDRYNRTNTLTFTIEERI------------MQLDKFDLSTYDKDIA--LLMLNGTV 160
            :...|.:|..:.:...:|     .:|:            |.|.|......|:|.:  |::|..:.
Human    69 KNSQVWLGRHNLFEPEDT-----GQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSE 128

  Fly   161 PT---------GHPTIRPIALNRFAIPEGVVCQVTGWGNTE-DGYVSD-ILMTVDVPMISEEHCI 214
            |.         |.||..| ||       |..|..:|||:.| :.::.. .|..|.:.::|.:.|.
Human   129 PAKITDVVKVLGLPTQEP-AL-------GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185

  Fly   215 NDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSELAGVVSWGIQ-CALPRLPGVYTEVS 278
            .  .....:...|:||| |..|.||.|.|||||||||...|.|:.|||.: ||||..|.|||:|.
Human   186 R--AYSEKVTEFMLCAG-LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVV 247

  Fly   279 YYYDWILQNMGEN 291
            :|..||...:..|
Human   248 HYRKWIKDTIAAN 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6048NP_572282.1 Tryp_SPc 45..284 CDD:214473 84/264 (32%)
KLK2NP_005542.1 Tryp_SPc 25..256 CDD:238113 85/266 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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