DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	251	Identity:	89/251 - (35%)
Similarity:	125/251 - (49%)	Gaps:	31/251 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPK 109
            |||.||:...|....||.:       :|.|:.: ||.|:|...|:|:|||||....:.|.|
Human   605 RIIGGTDTLEGGWPWQVSL-------HFVGSAY-CGASVISREWLLSAAHCFHGNRLSDPT---- 657

  Fly   110 EEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDKDIALLMLNGTVP-TGHPTIRPIAL- 172
                ....:|..|.:.|....:...||:..:.::..|:|.|||||.|:...| |....|:||.:
Human   658 ----PWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIP 718

  Fly   173 -NRFAIPEGVVCQVTGWG--NTEDGYVSDILMTVDVPMISEEHCINDSDLGHLIQPGMICAGYLE 234
             ....:..|..|.|||||  :..|...|.:|...:|.:|.:..|:  |..| :|...|:|||.:.
Human   719 PTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCV--STYG-IITSRMLCAGIMS 780

  Fly   235 VGEKDACAGDSGGPLVCQSE------LAGVVSWGIQCALPRLPGVYTEVSYYYDWI 284
             |::|||.|||||||.|:.:      |.|:||||.....|..|||||.||.:..||
Human   781 -GKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	87/249 (35%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920