DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6048 and Prss53

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	297	Identity:	84/297 - (28%)
Similarity:	131/297 - (44%)	Gaps:	45/297 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 HLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTLTFTIEE---RIMQ 138
            |:|.|||:...|||||||||......:     ...:.||:|:|.:..::.    ..||   ..:|
Mouse    60 HICSGSLVADTWVLTAAHCFEKMATAE-----LSSWSVVLGSLKQEGQSP----GAEEVGVAALQ 115

  Fly   139 LDK-FDLSTYDKDIALLMLNGTVPTGHPTIRP---IALNRFAIPEGVVCQVTGWG-NTEDGYVSD 198
            |.| ::..:...|:|||.|.      |||::.   :....:..|.|..|..|||. ||.|  ||.
Mouse   116 LPKAYNHYSQGSDLALLQLT------HPTVQTTLCLPQPTYHFPFGASCWATGWDQNTSD--VSR 172

  Fly   199 ILMTVDVPMISEEHC------INDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSE--- 254
            .|..:.:.:||...|      ::...|.:..:|||:|.| .:.||:..|.||||||::|:..
Mouse   173 TLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGG-AQPGEQGPCQGDSGGPVMCREPDGH 236

  Fly   255 --LAGVVSWGIQCALPRLPGVYTEVSYYYDWILQNMGE-----NGEGSGEESGEGSGEGSGEGSG 312
              ..|::|:..:||....|.:.|:::.:..|:..::.|     ...|..:.|.|.|....|....
Mouse   237 WVQVGIISFTSKCAQEDTPVLLTDMAVHSSWLQAHVHEAAFLVQAPGVVKMSDENSCVACGSLRS 301

  Fly   313 EGSGEGSGDDGSGD---DEDGSGDGGGAMAAVAGSLT 346
            .|...|:......|   ...|....|||:.:....||
Mouse   302 AGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLT 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	68/225 (30%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113	69/228 (30%)
		Tryp_SPc	311..522	CDD:238113	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010