DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	104/279 - (37%)
Similarity:	148/279 - (53%)	Gaps:	31/279 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LRGATTRTHLDT---KAIRPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGS 82
            :|...|..|:.|   .|...|....| ||:.|..:||.....||.::   ..||     ||||||
  Rat   190 MREGCTSGHVVTLKCSACGMRTGYSP-RIVGGNVSSLTQWPWQVSLQ---FQGY-----HLCGGS 245

  Fly    83 LIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTY 147
            :|.|.|::|||||     :|| .:.|| .:.|.:|.:...:  :.:...:.|:|:...|:.....
  Rat   246 VITPLWIVTAAHC-----VYD-LYHPK-SWTVQVGLVSLMD--SPVPSHLVEKIIYHSKYKPKRL 301

  Fly   148 DKDIALLMLNGTVPTGHPTIRPIAL--NRFAIPEGVVCQVTGWGNTEDGY--VSDILMTVDVPMI 208
            ..||||:.|:..: |...||:||.|  :....|:|.:|..:|||.||||.  .|.:|....||:|
  Rat   302 GNDIALMKLSEPL-TFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLI 365

  Fly   209 SEEHCINDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQS----ELAGVVSWGIQCALPR 269
            |.:.|.:....|.:|.|.|:|||||: |..|:|.||||||||||.    :|.|..|:||.||...
  Rat   366 SNKICNHRDVYGGIISPSMLCAGYLK-GGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVN 429

  Fly   270 LPGVYTEVSYYYDWILQNM 288
            .|||||.::.:.|||.:.:
  Rat   430 KPGVYTRITSFLDWIHEQL 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	95/246 (39%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	5/20 (25%)
		Tryp_SPc	216..444	CDD:214473	95/246 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910