DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and HABP2

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_004123.1	Gene:	HABP2 / 3026	HGNCID:	4798	Length:	560	Species:	Homo sapiens

Alignment Length:	257	Identity:	87/257 - (33%)
Similarity:	128/257 - (49%)	Gaps:	36/257 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPK 109
            ||..|.:::.|....|..::.:|........||.|||:||.|.||||||||         |.:..
Human   313 RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHC---------TDIKT 368

  Fly   110 EEFIVVMGNLD-RYNRTNTLTFTIEERIMQLDKFDLSTYDK-------DIALLMLNGTVPTGH-- 164
            ....||:|:.| :....:..:|.:|:      .|..|.|::       |||||.|...  .||
Human   369 RHLKVVLGDQDLKKEEFHEQSFRVEK------IFKYSHYNERDEIPHNDIALLKLKPV--DGHCA 425

  Fly   165 ---PTIRPIALNRFAIPEGVVCQVTGWGNTEDGYVSDILMTVDVPMISEEHCINDSDLGHLIQPG 226
               ..::.:.|...:.|.|..|.::|||.||.|..|..|:...|.:|:...|.:.....|:|...
Human   426 LESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDS 490

  Fly   227 MICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGIQCALPRLPGVYTEVSYYYDWI 284
            |||||.|:...:|.|.|||||||.|:.:    :.|:||||::|.  :.|||||:|:.:.:||
Human   491 MICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECG--KRPGVYTQVTKFLNWI 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	85/255 (33%)
HABP2	NP_004123.1	EGF	77..106	CDD:306513
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	86/256 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6411
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860