DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	97/284 - (34%)
Similarity:	133/284 - (46%)	Gaps:	52/284 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TRTHLDTKAIRPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVL 90
            :|.::..:.......|..|||:.|...|......||.:.        |||.|:|||:||...|||
  Rat   278 SRRYVSLQCAHCGLRAMTGRIVGGALTSESKWPWQVSLH--------FGTTHICGGTLIDAQWVL 334

  Fly    91 TAAHCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTL-----TFTIEERIMQ---LDKFDLSTY 147
            ||||||         ||.:|:   ::.....|..|:.|     ..:|.:.|:.   .|:.|
  Rat   335 TAAHCF---------FVTREK---ILEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQD---- 383

  Fly   148 DKDIALLMLNGTVPTG---HPTIRPIALNRFAIPEGVVCQVTGWGNTE--DGYVSDILMTVDVPM 207
            |.||||:.|:..:...   ||...|:....|.:.|  .|.:||:|.|:  |...|..|..|.|.:
  Rat   384 DYDIALVRLSKPLTLSAHIHPACLPLHGQTFGLNE--TCWITGFGKTKETDEKTSPFLREVQVNL 446

  Fly   208 ISEEHC----INDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGIQ 264
            |..:.|    :.||    .:.|.|:|||.|. |.:|:|.|||||||||:..    ||||.|||..
  Rat   447 IDFKKCNDYLVYDS----YLTPRMMCAGDLR-GGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTG 506

  Fly   265 CALPRLPGVYTEVSYYYDWILQNM 288
            |.....|||||:|:....||.:.|
  Rat   507 CGQKNKPGVYTKVTEVLPWIYRKM 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	91/259 (35%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964
		SRCR_2	203..292	CDD:292133	1/13 (8%)
		SRCR	216..288	CDD:278931	1/9 (11%)
		Tryp_SPc	297..526	CDD:214473	91/259 (35%)
		Tryp_SPc	298..526	CDD:238113	90/258 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910