DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6048 and PRSS55

DIOPT Version :9

Sequence 1:	NP_572282.1	Gene:	CG6048 / 31528	FlyBaseID:	FBgn0029827	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_940866.2	Gene:	PRSS55 / 203074	HGNCID:	30824	Length:	352	Species:	Homo sapiens

Alignment Length:	273	Identity:	92/273 - (33%)
Similarity:	122/273 - (44%)	Gaps:	63/273 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQI 100
            |.|::    ||..|.||.:|....||.| :|.::.:       ||||::...|:||||||
Human    62 RTRYS----RITGGMEAEVGEFPWQVSI-QARSEPF-------CGGSILNKWWILTAAHC----- 109

  Fly   101 IYDGTFVPKEEFIVVMGNLDRYNRTNTLT---FTIEE--RIMQLDKFDLSTYDKDIALLMLNGTV 160
            :|.....| ||..||:|       ||.||   ..|:|  .|:....|..:..|.|||||:|
Human   110 LYSEELFP-EELSVVLG-------TNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLL---- 162

  Fly   161 PTGHPTIRPIALNRFAIP------EGVV----CQVTGWGNT---EDGYVSDILMTVDVPMISEEH 212
                  ..||.|:...:|      .|..    |.|.|||.|   :...|...||...:.::..|.
Human   163 ------ASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEE 221

  Fly   213 CINDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSE------LAGVVSWGIQCALPRLP 271
            |   |.:...:...|:|||| :....|||.|||||||||..|      ..|::|||..|.....|
Human   222 C---SKMFPKLTKNMLCAGY-KNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTP 282

  Fly   272 GVYTEVSYYYDWI 284
            |:||.:..|..||
Human   283 GIYTSLVNYNLWI 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	88/262 (34%)
PRSS55	NP_940866.2	Tryp_SPc	67..295	CDD:214473	88/262 (34%)
		Tryp_SPc	68..298	CDD:238113	89/263 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910