Protein Alignment CG6041 and KLK4

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 83/269 - (30%)
• Similarity: 127/269 - (47%)
• Gaps: 39/269 - (14%)

  Fly     5 WAILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCG 69
            :.||.:|   |:|.||..          .:|:.|.|.|.....:|.:: :..|:.       .|.
Human    14 YLILGVA---GSLVSGSC----------SQIINGEDCSPHSQPWQAAL-VMENEL-------FCS 57

  Fly    70 GVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTD-RTLMYYLQQLITHENYNPDA 133
            ||::..:.|.:||||          ....:.:.:|...|.:..: .:.|......:.|..||...
Human    58 GVLVHPQWVLSAAHC----------FQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPL 112

  Fly   134 LTNDIALMFINGYIPWNWPTVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPIVS 198
            |.||:.|:.::..:..: .|:.::::.||.......||:|||||| .||...: .||...|.:||
Human   113 LANDLMLIKLDESVSES-DTIRSISIASQCPTAGNSCLVSGWGLL-ANGRMPT-VLQCVNVSVVS 174

  Fly   199 YTTCRISYNSI--PVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYG-AGCAAPGYPGVYT 260
            ...|...|:.:  | |..|||......|:|.||||||:.|||.|.|:||:| |.|...|.|||||
Human   175 EEVCSKLYDPLYHP-SMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYT 238

  Fly   261 NVSYYYDWI 269
            |:..:.:||
Human   239 NLCKFTEWI 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	74/238 (31%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	76/239 (32%)