Protein Alignment CG6041 and PRSS22

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 85/275 - (30%)
• Similarity: 128/275 - (46%)
• Gaps: 30/275 - (10%)

  Fly    34 KIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVISQRLVATAAHCCYITDKKKYRTAGE 98
            ::|||.|::..:..:.|||:....        |.|.|.:::.|.|.|||||......|.|.
Human   157 RVVGGEDSTDSEWPWIVSIQKNGT--------HHCAGSLLTSRWVITAAHCFKDNLNKPYL---- 209

  Fly    99 FVLVMGSTYLTSSTDRTLMYYLQQLITHENYN-PDALTNDIALMFINGYIPWNWPTVTALALNSQ 162
            |.:::|:..|.:...|:....:..:..|..|: .:....||||:.:...|.::...:.....::.
Human   210 FSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDAS 274

  Fly   163 L-VATNTDCLISGWGLLQQNGTF-SSNTLQAATVPIVSYTTCRISY------NSIPVSQVCAGYL 219
            : :..||.|.|||||.:|..... ...|||...|||:....|...|      ..|....:|||||
Human   275 IHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYL 339

  Fly   220 SGGVDACQGDSGGPMSCN----GMLAGIVSYGAGCAAPGYPGVYTNVSYYYDWI--VQKNSSLNY 278
            .|..|||.||||||:.|.    .:||||:|:|.|||....||||.::|.:..|:  :.:...|..
Human   340 EGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRG 404

  Fly   279 TIYHNGGVR---QGS 290
            .....|.:|   |||
Human   405 RAQGGGALRAPSQGS 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	78/247 (32%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	79/249 (32%)