Protein Alignment CG6041 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 98/307 - (31%)
• Similarity: 146/307 - (47%)
• Gaps: 57/307 - (18%)

  Fly    14 LGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVISQRLV 78
            |..||.|:||.:       |::||..:||::...:||||:        |...|:|||.::....|
Human   191 LHCLACGKSLKT-------PRVVGVEEASVDSWPWQVSIQ--------YDKQHVCGGSILDPHWV 240

  Fly    79 ATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNP----DALTNDIA 139
            .|||||.     :|:.....:.:..||..|.|.....    :.::|..| :||    |   ||||
Human   241 LTAAHCF-----RKHTDVFNWKVRAGSDKLGSFPSLA----VAKIIIIE-FNPMYPKD---NDIA 292

  Fly   140 LMFINGYIPWNWPTVTALAL---NSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPIVSYTT 201
            ||.:...:.:: .||..:.|   :.:|... |...|.|||..:|||...|:.|..|:|.::..|.
Human   293 LMKLQFPLTFS-GTVRPICLPFFDEELTPA-TPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTR 355

  Fly   202 CRIS---YNSIPVSQVCAGYLSGGVDACQGDSGGPM---SCNGMLAGIVSYGAGCAAPGYPGVYT 260
            |...   ...:....:|||...||||.||||||||:   |....:.||||:|.||..|..|||||
Human   356 CNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT 420

  Fly   261 NVSYYYDWIVQKNSSLNYTIYHNGGVRQGSSWSYLGI------LPLL 301
            .||.|.:||        |.::.:..:::..:....|:      :||:
Human   421 KVSAYLNWI--------YNVWKDRTIQRSCNSPGTGLVIQQPAVPLM 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	85/247 (34%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	3/5 (60%)
		Tryp_SPc	204..429	CDD:214473	85/247 (34%)