Protein Alignment CG6041 and KLK6

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 87/266 - (32%)
• Similarity: 118/266 - (44%)
• Gaps: 36/266 - (13%)

  Fly     8 LAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGH-LCGGV 71
            |.:.|.|.|.|..|.         :.|:|.|.........||.::         |.||| |||||
Human     4 LMVVLSLIAAAWAEE---------QNKLVHGGPCDKTSHPYQAAL---------YTSGHLLCGGV 50

  Fly    72 VISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDALTN 136
            :|....|.|||||     ||.     ...:.:|...|...........:.:.:.|.:|  ||.::
Human    51 LIHPLWVLTAAHC-----KKP-----NLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY--DAASH 103

  Fly   137 DIALMFINGYIPWNW-PTVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPIVSYT 200
            |..:|.:....|... ..:..|.|.....|..|.|.|.||| ...:|.| .:|:|.|.:.:||..
Human   104 DQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWG-KTADGDF-PDTIQCAYIHLVSRE 166

  Fly   201 TCRISY-NSIPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYG-AGCAAPGYPGVYTNVS 263
            .|..:| ..|..:.:|||....|.|:||||||||:.|...|.|:||:| ..|.:...|||||||.
Human   167 ECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC 231

  Fly   264 YYYDWI 269
            .|.:||
Human   232 RYTNWI 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	79/238 (33%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	78/236 (33%)