Protein Alignment CG6041 and PLAT

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 82/261 - (31%)
• Similarity: 124/261 - (47%)
• Gaps: 39/261 - (14%)

  Fly    34 KIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVISQRLVATAAHCCYITDKKKYRTAGE 98
            :|.||..|.|....:|.:|  .|..::|.|...||||::||...:.:||||........:.|
Human   310 RIKGGLFADIASHPWQAAI--FAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT--- 369

  Fly    99 FVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDALTNDIALMFINGYIPWNWPTVTALALNSQL 163
              :::|.||.....:....:.:::.|.|:.::.|...|||||:.:..       ..:..|..|.:
Human   370 --VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKS-------DSSRCAQESSV 425

  Fly   164 VATN------------TDCLISGWGLLQQNGTFSSNTLQAATVPIVSYTTCRISY---NSIPVSQ 213
            |.|.            |:|.:||:|..:....|.|..|:.|.|.:...:.|...:   .::..:.
Human   426 VRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNM 490

  Fly   214 VCAG-YLSGGV-----DACQGDSGGPMSC--NG--MLAGIVSYGAGCAAPGYPGVYTNVSYYYDW 268
            :||| ..|||.     ||||||||||:.|  :|  .|.||:|:|.||.....|||||.|:.|.||
Human   491 LCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDW 555

  Fly   269 I 269
            |
Human   556 I 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	80/259 (31%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113	81/258 (31%)