Protein Alignment CG6041 and KLK12

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 89/304 - (29%)
• Similarity: 131/304 - (43%)
• Gaps: 65/304 - (21%)

  Fly     8 LAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVV 72
            |:|.|.|..|...::.:        |||..|.:.......:||.:        ..|:...||||:
Human     3 LSIFLLLCVLGLSQAAT--------PKIFNGTECGRNSQPWQVGL--------FEGTSLRCGGVL 51

  Fly    73 ISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTL--MYYLQQL------ITHENY 129
            |..|.|.|||||                  .||.|.....:.:|  :.:.:|:      :||..|
Human    52 IDHRWVLTAAHC------------------SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY 98

  Fly   130 NPDALTNDIALMFINGYIPWN-WPTVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAAT 193
            ...:.:::..|..:...:|.. ..:|..|.|.:......|:|.:||||:.........:.||...
Human    99 LGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLN 163

  Fly   194 VPIVSYTTCRISY-NSIPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYGA--GCAAPGY 255
            :.|||:.||...| ..|..:.||||.:. |.||||||||||:.|.|:|.|:||:|:  .|...|.
Human   164 LSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGI 227

  Fly   256 PGVYTNVSYYYDWIVQKNSSLNYTIYHNGGVRQGSSWSYLGILP 299
            |||||.:.         ||:|         |..|:||::....|
Human   228 PGVYTYIC---------NSTL---------VGLGTSWNFNSCQP 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	75/246 (30%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	74/249 (30%)