Protein Alignment CG6041 and KLK14

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 90/274 - (32%)
• Similarity: 128/274 - (46%)
• Gaps: 43/274 - (15%)

  Fly     7 ILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGV 71
            :|..||.:.|:|..:|...|.      ||:||:..:.....:|.:  |.|..::.:    ||||.
Human     3 LLLTALQVLAIAMTQSQEDEN------KIIGGHTCTRSSQPWQAA--LLAGPRRRF----LCGGA 55

  Fly    72 VISQRLVATAAHCCYITDKKKYRTAGEFVL--VMGSTYLT--SSTDRTLMYYLQQLITHENYNPD 132
            ::|.:.|.|||||            |..:|  .:|...|.  .:|.:.|....|  :||.|||..
Human    56 LLSGQWVITAAHC------------GRPILQVALGKHNLRRWEATQQVLRVVRQ--VTHPNYNSR 106

  Fly   133 ALTNDIALMFINGYIPWNWP-----TVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAA 192
            ...||:.|:.:      ..|     .|..:.:.....:..|.|.:||||.:.........:||..
Human   107 THDNDLMLLQL------QQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCV 165

  Fly   193 TVPIVSYTTCRISY-NSIPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYG-AGCAAPGY 255
            .:.|.....|:.:| .:|....||||...||.|:||||||||:.|.|.|.|:||:| ..||.|||
Human   166 NINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGY 230

  Fly   256 PGVYTNVSYYYDWI 269
            ||||||:..|..||
Human   231 PGVYTNLCKYRSWI 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	81/245 (33%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	82/246 (33%)