Protein Alignment CG6041 and KLKB1

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 99/279 - (35%)
• Similarity: 142/279 - (50%)
• Gaps: 39/279 - (13%)

  Fly    18 ASGESL-------SSETAGKIEPKIVGGYDASIEQVSYQVS--IRLTANDKKSYGSGHLCGGVVI 73
            :||.||       :|....|...:||||.::|..:..:|||  ::|||       ..|||||.:|
Human   378 SSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTA-------QRHLCGGSLI 435

  Fly    74 SQRLVATAAHC---CYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDALT 135
            ..:.|.|||||   ..:.|..:        :..|...|:..|..|....::::|.|:||......
Human   436 GHQWVLTAAHCFDGLPLQDVWR--------IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGN 492

  Fly   136 NDIALMFIN---GYIPWNWPTVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPIV 197
            :||||:.:.   .|..:..|.......::..:.||  |.::|||..::.|.. .|.||...:|:|
Human   493 HDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTN--CWVTGWGFSKEKGEI-QNILQKVNIPLV 554

  Fly   198 SYTTCRISYNSIPVSQ--VCAGYLSGGVDACQGDSGGPMSC--NGM--LAGIVSYGAGCAAPGYP 256
            :...|:..|....::|  |||||..||.|||:||||||:.|  |||  |.||.|:|.|||....|
Human   555 TNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQP 619

  Fly   257 GVYTNVSYYYDWIVQKNSS 275
            ||||.|:.|.|||::|..|
Human   620 GVYTKVAEYMDWILEKTQS 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	89/248 (36%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519	4/7 (57%)
		Tryp_SPc	402..632	CDD:238113	89/247 (36%)