Protein Alignment CG6041 and KLK2

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 89/287 - (31%)
• Similarity: 134/287 - (46%)
• Gaps: 55/287 - (19%)

  Fly     4 VW-AILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHL 67
            :| .:|:|||.:|...:        ...|:.:||||::.......:||::       .|:|..|
Human     1 MWDLVLSIALSVGCTGA--------VPLIQSRIVGGWECEKHSQPWQVAV-------YSHGWAH- 49

  Fly    68 CGGVVISQRLVATAAHCCYITDKKKYRT------------AGEFVLVMGSTYLTSSTDRTLMYYL 120
            ||||::..:.|.|||||.    ||..:.            .|:.|.|      :.|....|  |.
Human    50 CGGVLVHPQWVLTAAHCL----KKNSQVWLGRHNLFEPEDTGQRVPV------SHSFPHPL--YN 102

  Fly   121 QQLITHENYNPDA-LTNDIALMFINGYIPWNWP-----TVTALALNSQLVATNTDCLISGWGLLQ 179
            ..|:.|::..||. .::|:.|:.::.      |     .|..|.|.:|..|..|.|..||||.::
Human   103 MSLLKHQSLRPDEDSSHDLMLLRLSE------PAKITDVVKVLGLPTQEPALGTTCYASGWGSIE 161

  Fly   180 QNGTFSSNTLQAATVPIVSYTTCRISYN-SIPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGI 243
            ........:||..::.::|...|..:|: .:....:|||..:||.|.|.||||||:.|||:|.||
Human   162 PEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGI 226

  Fly   244 VSYG-AGCAAPGYPGVYTNVSYYYDWI 269
            .|:| ..||.|..|.|||.|.:|..||
Human   227 TSWGPEPCALPEKPAVYTKVVHYRKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	80/254 (31%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	82/255 (32%)