Protein Alignment CG6041 and KLK1

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 75/288 - (26%)
• Similarity: 125/288 - (43%)
• Gaps: 43/288 - (14%)

  Fly     4 VW-AILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHL 67
            :| .:|.:||.||...:        |..|:.:||||::.......:|.::        .:.|...
Human     1 MWFLVLCLALSLGGTGA--------APPIQSRIVGGWECEQHSQPWQAAL--------YHFSTFQ 49

  Fly    68 CGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPD 132
            |||:::.::.|.|||||  |:|        .:.|.:|...|....:.....::.:...|..:|..
Human    50 CGGILVHRQWVLTAAHC--ISD--------NYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMS 104

  Fly   133 ALTN-----------DIALMFINGYIPWNWPTVTALALNSQLVATNTDCLISGWGLLQQNGTFSS 186
            .|.|           |:.|:.:..........|..:.|.::.....:.||.||||.::.......
Human   105 LLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFP 169

  Fly   187 NTLQAATVPIVSYTTCRISY-NSIPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYG-AG 249
            :.||...:.|:....|:.:: ..:....:|.|:|.||.|.|.||||||:.|:|:|.|:.|:| ..
Human   170 DDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVP 234

  Fly   250 CAAPGYPGVYTNVSYYYDWI---VQKNS 274
            |..|..|.|...|..|..||   :.:||
Human   235 CGTPNKPSVAVRVLSYVKWIEDTIAENS 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	63/247 (26%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	65/249 (26%)