Protein Alignment CG6041 and PRSS53

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 78/329 - (23%)
• Similarity: 121/329 - (36%)
• Gaps: 80/329 - (24%)

  Fly     5 WAILAIALFLGALASGESLSSE-----TAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGS 64
            |....:.|..||....|.|.:.     ..|...||...|.....|. .:|.|:|..        .
Human     3 WCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEW-PWQASVRRQ--------G 58

  Fly    65 GHLCGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTY---LTSSTDRTLMYYLQQLITH 126
            .|:|.|.:::...|.|||||   .:|........:.:|:||..   |:...:...:..||....:
Human    59 AHICSGSLVADTWVLTAAHC---FEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAY 120

  Fly   127 ENYNPDALTNDIALM-------------------FINGYIPWN------------WPTV---TAL 157
            .:|:..   :|:||:                   |..|...|.            ||.:   .||
Human   121 NHYSQG---SDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEAL 182

  Fly   158 ALNSQLVATNTDCLISGWGLLQQNGTF--------SSNTLQAATVPIVSYTTCRISYNSI----- 209
            .|.|..|:. .:|......||.::.|.        :..||:...:.::|..||...||.:
Human   183 CLPSVTVSA-PNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQLHQRHL 246

  Fly   210 --PV--SQVCAGYLSGGVDACQGDSGGPMSC-----NGMLAGIVSYGAGCAAPGYPGVYTNVSYY 265
              |.  ..:|.|...|....||||||||:.|     :.:.|||:|:.:.||....|.:.||.:.:
Human   247 SNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAH 311

  Fly   266 YDWI 269
            ..|:
Human   312 SSWL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	69/293 (24%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	68/290 (23%)
		Tryp_SPc	359..>512	CDD:473915