Protein Alignment CG6041 and HGFAC

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 81/285 - (28%)
• Similarity: 124/285 - (43%)
• Gaps: 52/285 - (18%)

  Fly    14 LGALASGESLSSETAGK-------IEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGV 71
            |..|....|...:..|:       :.|:|:||..:......:..:|         |.....|.|.
Human   387 LATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAI---------YIGDSFCAGS 442

  Fly    72 VISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENY---NPDA 133
            ::....|.:||||...:..:     ....:|:|..:...:||.|..:.:::.|.:..|   ||.
Human   443 LVHTCWVVSAAHCFSHSPPR-----DSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPS- 501

  Fly   134 LTNDIALMFINGYIPWNWPTVTALALNSQLV------------ATNTDCLISGWGLLQQNGTFSS 186
             .:|:.|:.:.       ......|..||.|            .....|.|:|||.|.:|.:..|
Human   502 -DHDLVLIRLK-------KKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYS 558

  Fly   187 NTLQAATVPIVSYTTC---RISYNSIPVSQVCAGYLSGGVDACQGDSGGPMSC--NGM--LAGIV 244
            ::|:.|.||:|:...|   .:....|..:.:||||.....||||||||||::|  ||:  |.||:
Human   559 SSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGII 623

  Fly   245 SYGAGCAAPGYPGVYTNVSYYYDWI 269
            |:|.||.....|||||.|:.|.|||
Human   624 SWGDGCGRLHKPGVYTRVANYVDWI 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	74/256 (29%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	76/257 (30%)