DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6041 and F12

DIOPT Version :9

Sequence 1:	NP_572281.1	Gene:	CG6041 / 31527	FlyBaseID:	FBgn0029826	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001014028.1	Gene:	F12 / 306761	RGDID:	1359175	Length:	603	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	80/256 - (31%)
Similarity:	119/256 - (46%)	Gaps:	39/256 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVISQRLVATAAHCCYITDKKKYRTAGE 98
            ::|||..|......|..::         |.....|.|.:|....|.|||||.     :|.....|
  Rat   361 RVVGGLVALPGSHPYIAAL---------YWGDSFCAGSLIDPCWVLTAAHCL-----QKRPAPEE 411

  Fly    99 FVLVMGSTYLTSSTDR--TLMYYLQQLITHENYNPDALTNDIALMFING------YIPWNWPTVT 155
            ..:|:|......|.:|  ||..:..:|  ||.::.....:|:||:.:.|      .:.   |.|.
  Rat   412 LTVVLGQDRHNQSCERCQTLAVHSYRL--HEGFSSKTYQHDLALLRLRGRKNSCAILS---PHVQ 471

  Fly   156 ALALNSQLVATNTD--CLISGWGLLQQNGTFSSNTLQAATVPIVSYTTC---RISYNSIPVSQVC 215
            .:.|.|.....:..  |.::|||...:.....:..||.|.||.:|...|   .:..::|....:|
  Rat   472 PVCLPSSAAPPSETVLCEVAGWGHQFEGAEEYATFLQEAQVPFISLDRCSSSNVHGDAILPGMLC 536

  Fly   216 AGYLSGGVDACQGDSGGPMSCN-GM------LAGIVSYGAGCAAPGYPGVYTNVSYYYDWI 269
            ||:|.||.||||||||||:.|: |:      |.|::|:|:||.....|||||:|:.|.|||
  Rat   537 AGFLEGGADACQGDSGGPLVCDEGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWI 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	78/254 (31%)
CG6041	NP_572281.1	Tryp_SPc	35..272	CDD:238113	80/255 (31%)
F12	NP_001014028.1	FN2	40..87	CDD:238019
		EGF_CA	95..130	CDD:238011
		FN1	132..170	CDD:238018
		EGF	177..207	CDD:278437
		Kringle	216..294	CDD:278480
		Tryp_SPc	361..597	CDD:214473	78/254 (31%)
		Tryp_SPc	362..600	CDD:238113	80/255 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910