Protein Alignment CG6041 and GZMM

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 89/279 - (31%)
• Similarity: 132/279 - (47%)
• Gaps: 43/279 - (15%)

  Fly     2 AKVWAILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGH 66
            |.|.::|.:|  ||||:.|.|..::        |:||.:.......|..|::...:        |
Human     3 ACVSSLLVLA--LGALSVGSSFGTQ--------IIGGREVIPHSRPYMASLQRNGS--------H 49

  Fly    67 LCGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNP 131
            |||||::..:.|.|||||.       .:...:..||:|...|.|.   .|.::::..|.|..|.|
Human    50 LCGGVLVHPKWVLTAAHCL-------AQRMAQLRLVLGLHTLDSP---GLTFHIKAAIQHPRYKP 104

  Fly   132 -DALTNDIALMFINGYIPWNWP--TVTALALNS--QLVATNTDCLISGWGLLQQNGTFSSNTLQA 191
             .||.||:||:.::|.:.   |  |:..|||.|  |:||..|.|.::||||..|.|.. |..|:.
Human   105 VPALENDLALLQLDGKVK---PSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRL-SRVLRE 165

  Fly   192 ATVPIVSYTTC---RISYNSIPVSQVCAGYLSGGVDACQGDSGGPMSC--NGMLAGIVSYGAG-C 250
            ..:.::....|   |....|:..|.||....|.....|:||||||:.|  ..:||.::|:.:. |
Human   166 LDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLARVLSFSSRVC 230

  Fly   251 AAPGYPGVYTNVSYYYDWI 269
            .....|.|.|.|:.|..||
Human   231 TDIFKPPVATAVAPYVSWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	77/245 (31%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	79/246 (32%)