Protein Alignment CG6041 and GZMK

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 84/285 - (29%)
• Similarity: 124/285 - (43%)
• Gaps: 47/285 - (16%)

  Fly     1 MAKVWAILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSG 65
            |.|..:.....|.:||..:....:.|        |:||.:.|.....:..||:        ||..
Human     1 MTKFSSFSLFFLIVGAYMTHVCFNME--------IIGGKEVSPHSRPFMASIQ--------YGGH 49

  Fly    66 HLCGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYN 130
            |:||||:|..:.|.|||||.|...|.:..|     :|:|:..|:.:........:::.|......
Human    50 HVCGGVLIDPQWVLTAAHCQYRFTKGQSPT-----VVLGAHSLSKNEASKQTLEIKKFIPFSRVT 109

  Fly   131 PDALTNDIALMFINGYIPWNWPTVTALALNSQL----------VATNTDCLISGWGLLQQNGTFS 185
            .|..:|||.|:.:.          ||..||..:          :.:.|.|.::|||....:....
Human   110 SDPQSNDIMLVKLQ----------TAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRP 164

  Fly   186 SNTLQAATVPIVSYTTCRIS--YNSIPV---SQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVS 245
            |:||:..||.::|...|...  ||..|.   ..||||...|..|:|:||||||:.|.|:...|||
Human   165 SDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVS 229

  Fly   246 YGAGCAAPGYPGVYTNVS-YYYDWI 269
            .|..|.....||:||.:: .|..||
Human   230 GGHECGVATKPGIYTLLTKKYQTWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	76/250 (30%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	78/251 (31%)