Protein Alignment CG6041 and F10

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 79/291 - (27%)
• Similarity: 124/291 - (42%)
• Gaps: 57/291 - (19%)

  Fly    18 ASGESLSSET-----AGKIEP-----------------------KIVGGYDASIEQVSYQVSIRL 54
            :|||:..|.|     |..::|                       :||||.:....:..:|.   |
Human   190 SSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQA---L 251

  Fly    55 TANDKKSYGSGHLCGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYY 119
            ..|::..    ..|||.::|:..:.|||||.|...:.|.|        :|............::.
Human   252 LINEENE----GFCGGTILSEFYILTAAHCLYQAKRFKVR--------VGDRNTEQEEGGEAVHE 304

  Fly   120 LQQLITHENYNPDALTNDIALMFINGYIPWNWPTVTALA-----LNSQLVATNTDCLISGWGLLQ 179
            ::.:|.|..:..:....|||::.:...|.:......|..     ..|.|:...|. ::||:|...
Human   305 VEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTG-IVSGFGRTH 368

  Fly   180 QNGTFSSNTLQAATVPIVSYTTCRISYNSIPVSQ--VCAGYLSGGVDACQGDSGGP----MSCNG 238
            :.|. .|..|:...||.|...:|::| :|..::|  .||||.:...||||||||||    .....
Human   369 EKGR-QSTRLKMLEVPYVDRNSCKLS-SSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTY 431

  Fly   239 MLAGIVSYGAGCAAPGYPGVYTNVSYYYDWI 269
            .:.||||:|.|||..|..|:||.|:.:..||
Human   432 FVTGIVSWGEGCARKGKYGIYTKVTAFLKWI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	70/245 (29%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203		5/12 (42%)
		Tryp_SPc	235..464	CDD:238113	72/246 (29%)
		O-glycosylated at one site	476..485