Protein Alignment CG6041 and CFD

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 81/276 - (29%)
• Similarity: 139/276 - (50%)
• Gaps: 35/276 - (12%)

  Fly     5 WAILAIALFLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCG 69
            |..||:.:.|||.|.||. :...|.....:|:||.:|......|..|::|        ...||||
Human     4 WERLAVLVLLGAAACGEE-AWAWAAPPRGRILGGREAEAHARPYMASVQL--------NGAHLCG 59

  Fly    70 GVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDAL 134
            ||:::::.|.:||||  :.|    ...|:..:::|:..|:.......:|.:.:.:.|.:..||.:
Human    60 GVLVAEQWVLSAAHC--LED----AADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTI 118

  Fly   135 TNDIALMFIN-------GYIPWNWPTVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAA 192
            .:|:.|:.::       ...|..|..|      .:.||..|.|.::|||::...|. ..::||..
Human   119 DHDLLLLQLSEKATLGPAVRPLPWQRV------DRDVAPGTLCDVAGWGIVNHAGR-RPDSLQHV 176

  Fly   193 TVPIVSYTTC-RISYNSIPVSQ--VCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYGAG-CAAP 253
            .:|::...|| |.:::...:::  :||.  |...|:|:||||||:.|.|:|.|:|:.|:. |...
Human   177 LLPVLDRATCNRRTHHDGAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNR 239

  Fly   254 GYPGVYTNVSYYYDWI 269
            ..||:||.|:.|..||
Human   240 KKPGIYTRVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	69/245 (28%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	71/246 (29%)