DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6041 and PRSS36

DIOPT Version :9

Sequence 1:	NP_572281.1	Gene:	CG6041 / 31527	FlyBaseID:	FBgn0029826	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	260	Identity:	81/260 - (31%)
Similarity:	118/260 - (45%)	Gaps:	31/260 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GKIEP--KIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVISQRLVATAAHCCYITDKK 91
            |:.||  :||||.:|......:|||:.        :|.||:|||.:|:...|.:||| |::|: .
Human    39 GRPEPSARIVGGSNAQPGTWPWQVSLH--------HGGGHICGGSLIAPSWVLSAAH-CFMTN-G 93

  Fly    92 KYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDALTNDIALMFINGYI---PWNWPT 153
            ....|.|:.:::|........|......:..::...||:...|..|:||:.:....   |..||
Human    94 TLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWP- 157

  Fly   154 VTALALNSQLVATNTDCLISGWGLLQQNGTFSSN-TLQAATVPIVSYTTCRISYN---------S 208
             ..|...|......|.|..:|||.:|:....... .||...:.::...||:..|:         .
Human   158 -VCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQ 221

  Fly   209 IPVSQVCAGYLSGGVDACQGDSGGPMSC----NGMLAGIVSYGAGCAAPGYPGVYTNVSYYYDWI 269
            |....:||||..|..|.||||||||:.|    ....|||.|:|.||.....|||:|.|:.|..||
Human   222 ILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWI 286

Fly 270 269
Human 287 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	76/251 (30%)
CG6041	NP_572281.1	Tryp_SPc	35..272	CDD:238113	78/252 (31%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	76/251 (30%)
		Tryp_SPc	47..289	CDD:238113	78/252 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010