Protein Alignment CG6041 and Cfd

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 272
• Identity: 76/272 - (27%)
• Similarity: 132/272 - (48%)
• Gaps: 34/272 - (12%)

  Fly     6 AILAIAL-FLGALASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCG 69
            ::..:|| .|||        :..|.:...:|:||.:|:.....|..|:::...        |:||
Mouse     4 SVYFVALVILGA--------AVCAAQPRGRILGGQEAAAHARPYMASVQVNGT--------HVCG 52

  Fly    70 GVVISQRLVATAAHCC-YITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDA 133
            |.::.::.|.:||||. .:||....:      :::|:..|::.......|.:|.::.|....||:
Mouse    53 GTLLDEQWVLSAAHCMDGVTDDDSVQ------VLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDS 111

  Fly   134 LTNDIALMFINGYIPWNWPTVTALAL--NSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPI 196
            |.:|:.|..::...... |.|..|.|  ..:.|...|.|.::|||::...|. ..:.|....|.|
Mouse   112 LEDDLILFKLSQNASLG-PHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGR-RPDVLHQLRVSI 174

  Fly   197 VSYTTCRI-SYNS--IPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYGAG-CAAPGYPG 257
            ::.|||.: :|:.  :.::.:||.  |...|.|:||||.|:.|...:.|:|::|:. |.....||
Mouse   175 MNRTTCNLRTYHDGVVTINMMCAE--SNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPG 237

  Fly   258 VYTNVSYYYDWI 269
            |||.||.|..||
Mouse   238 VYTRVSSYRMWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	68/241 (28%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	70/242 (29%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)