Protein Alignment CG6041 and KLK8

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 80/257 - (31%)
• Similarity: 111/257 - (43%)
• Gaps: 31/257 - (12%)

  Fly    18 ASGESLSSETAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVISQRLVATAA 82
            |:|.|.:.      |.|::||::.......:|.::        ..|...|||||::....|.|||
Human    67 AAGHSRAQ------EDKVLGGHECQPHSQPWQAAL--------FQGQQLLCGGVLVGGNWVLTAA 117

  Fly    83 HCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHENYNPDAL---TNDIALMFIN 144
            ||    .|.||      .:.:|...|.:.........:.|.|.|..||...:   .:|:.|:.:.
Human   118 HC----KKPKY------TVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLR 172

  Fly   145 GYIPWNWPTVTALALNSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPIVSYTTCRISY-NS 208
            ...... ..|..::|..........|.:||||.:........:||..|.|.|.....|..:| ..
Human   173 DQASLG-SKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQ 236

  Fly   209 IPVSQVCAGYLSGGVDACQGDSGGPMSCNGMLAGIVSYGAG-CAAPGYPGVYTNVSYYYDWI 269
            |....|||| .|.|.|.||||||||:.|:|.|.||.|:|:. |.....||||||:..|.|||
Human   237 ITDGMVCAG-SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	74/239 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	74/239 (31%)