Protein Alignment CG6041 and PRSS21

DIOPT Version :10

• Sequence 1: NP_572281.1
• Gene: CG6041 / 31527
• FlyBaseID: FBgn0029826
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 104/330 - (31%)
• Similarity: 157/330 - (47%)
• Gaps: 57/330 - (17%)

  Fly     7 ILAIALFLGALASGESLS----SETAGK--IEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSG 65
            :||:.|....|...||..    |...|:  |..:||||.||.:.:..:|.|:||        ...
Human     8 LLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL--------WDS 64

  Fly    66 HLCGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLM--------YYLQQ 122
            |:||..::|.|...|||||        :.|..:  |...|.::......|.|        ||.:.
Human    65 HVCGVSLLSHRWALTAAHC--------FETYSD--LSDPSGWMVQFGQLTSMPSFWSLQAYYTRY 119

  Fly   123 LITHENYNPDALTN---DIALMFINGYIPWNWPTVTALALNSQL--VATNTDCLISGWGLLQQNG 182
            .:::...:|..|.|   ||||:.::..:.:. ..:..:.|.:..  ....|||.::|||.::::.
Human   120 FVSNIYLSPRYLGNSPYDIALVKLSAPVTYT-KHIQPICLQASTFEFENRTDCWVTGWGYIKEDE 183

  Fly   183 TF-SSNTLQAATVPIVSYTTCR---ISYN---SIPVSQVCAGYLSGGVDACQGDSGGPMSC--NG 238
            .. |.:|||...|.|::.:.|.   :.|:   .|....||||...||.|||.||||||::|  ||
Human   184 ALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNG 248

  Fly   239 M--LAGIVSYGAGCAAPGYPGVYTNVSYYYDWIVQKNSSLNYTIYHNGGVRQGSSWSYLGILPLL 301
            :  ..|:||:|.||..|..||||||:|::::|| ||      .:..:|..:...||..| ..|||
Human   249 LWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI-QK------LMAQSGMSQPDPSWPLL-FFPLL 305

  Fly   302 VAFLL 306
            .|..|
Human   306 WALPL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	82/258 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	84/260 (32%)