DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6041 and f12

DIOPT Version :9

Sequence 1:	NP_572281.1	Gene:	CG6041 / 31527	FlyBaseID:	FBgn0029826	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	94/285 - (32%)
Similarity:	142/285 - (49%)	Gaps:	47/285 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ASGESLSSETAGKIE--------------------PKIVGGYDASIEQVSYQVSIRLTANDKKSY 62
            ||..|.|::|.|.::                    |:||||..|......|..::         |
Frog   322 ASTPSPSNDTQGPVDGRIDLPVDCGRKFQKTPSIMPRIVGGLVALPASHPYIAAL---------Y 377

  Fly    63 GSGHLCGGVVISQRLVATAAHCCYITDKKKYRTAGEFVLVMGSTYLTSSTDRTLMYYLQQLITHE 127
            ...|.|||.:||...:.|||||   .|::...|  :..:|:|.:...::...|:...:::.|.||
Frog   378 IDNHFCGGSLISPCWIVTAAHC---LDQRPNVT--KISVVLGQSRFNTTDQHTVTLLVEKYILHE 437

  Fly   128 NYNPDALTNDIALM---FINGYIPWNWPT-VTALALNSQ--LVATNTDCLISGWGLLQQNGTFSS 186
            .|..|.|.:||||:   .|||.....:.. |..:.|..|  :..:...|:::|||...:.....:
Frog   438 KYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKMAESTKQCVVAGWGHQYEGAEHYA 502

  Fly   187 NTLQAATVPIVSYTTCR---ISYNSIPVSQVCAGYLSGGVDACQGDSGGPMSC--NGM--LAGIV 244
            ..||.|::||:.||.|:   :..:.:....:|||::.|||||||||||||:.|  :|.  |.|:|
Frog   503 FFLQEASMPIIPYTQCQSPSVHGDRMLPGMLCAGFMEGGVDACQGDSGGPLVCEVDGRIELHGVV 567

  Fly   245 SYGAGCAAPGYPGVYTNVSYYYDWI 269
            |:|:|||....|||||.|:.|.|||
Frog   568 SWGSGCAEENKPGVYTAVTSYTDWI 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6041	NP_572281.1	Tryp_SPc	34..269	CDD:214473	85/247 (34%)
CG6041	NP_572281.1	Tryp_SPc	35..272	CDD:238113	87/248 (35%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	87/248 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910