DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3726 and ZBTB37

DIOPT Version :9

Sequence 1:NP_001284917.1 Gene:CG3726 / 31525 FlyBaseID:FBgn0029824 Length:682 Species:Drosophila melanogaster
Sequence 2:NP_001116242.1 Gene:ZBTB37 / 84614 HGNCID:28365 Length:503 Species:Homo sapiens


Alignment Length:365 Identity:79/365 - (21%)
Similarity:134/365 - (36%) Gaps:96/365 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 SQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPIIIMKDVTFAEVKCLIE 86
            :||..:|..||:.:..:||..|||:|||.|.|.:|...:|........|.::|:.|..|.  |:.
Human    23 NQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQ--LLS 85

  Fly    87 FMYKGEINVEHSSLPSLLKTADDLKIK-----------------GLAEV------TWRDDEDGPP 128
            |.|.|.|.::.:.:.|.|..|..|:::                 .:|||      |....::.||
Human    86 FCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPP 150

  Fly   129 PPMAAAEFHSPPRSLAESYAQDLILQHQ--QQQQQGPAAPPLNLHSSAALLERDRERERERDRER 191
                  |.|....:|..|    |..:|.  :..::|..:..|::            ||.....|.
Human   151 ------ESHRVTPNLNRS----LSPRHNTPKGNRRGQVSAVLDI------------RELSPPEES 193

  Fly   192 LSPGM----EGVLGRMPVMT--------PLTGASGSAGVGS----VSGGTSLEGVAPVEHFLGPK 240
            .||.:    ..|..|.|::.        ..||.:...|...    |.|...:: ...:|.:|||:
Human   194 TSPQIIEPSSDVESREPILRINRAGQWYVETGVADRGGRSDDEVRVLGAVHIK-TENLEEWLGPE 257

  Fly   241 RKRGRPPLDDAYDVFNVRKLAQYAANLEPAQRAYLETARHFT---EEPPLAAHAASMASPPAA-- 300
               .:|..:|             .::.|......::|..|.:   |...|.:..|.:|.|.::  
Human   258 ---NQPSGED-------------GSSAEEVTAMVIDTTGHGSVGQENYTLGSSGAKVARPTSSEV 306

  Fly   301 ---------CPPKQRQRLRHQQQQQQQLLQSESSDQEQPA 331
                     .|..:|.|.|.:...:....:..||..|:.|
Human   307 DRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESA 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3726NP_001284917.1 BTB 21..118 CDD:279045 31/112 (28%)
BTB 32..121 CDD:197585 30/111 (27%)
HTH_psq 587..622 CDD:283007
ZBTB37NP_001116242.1 BTB_POZ_ZBTB37 7..129 CDD:349531 30/107 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 140..206 16/87 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 280..344 12/63 (19%)
C2H2 Zn finger 375..395 CDD:275368
zf-H2C2_2 387..412 CDD:404364
zf-C2H2 401..423 CDD:395048
C2H2 Zn finger 403..423 CDD:275368
zf-H2C2_2 416..438 CDD:404364
C2H2 Zn finger 431..449 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 457..503
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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