DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3726 and klhl24

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001072337.1	Gene:	klhl24 / 779790	XenbaseID:	XB-GENE-1000313	Length:	600	Species:	Xenopus tropicalis

Alignment Length:	164	Identity:	39/164 - (23%)
Similarity:	79/164 - (48%)	Gaps:	13/164 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPIIIMKDVT 77
            |..::..:|::..:...|.||.:..||:....||.:|.|||::|.|:..|...|...:::..:..
Frog    48 HSESILQVFNEFRENRLFTDVIICVEGREFPCHRAILSACSSYFRAMFCNDHRESREMLVEINGI 112

  Fly    78 FAE-VKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPMAA-----AEF 136
            ||| :.|.::::|.|.:.:...::..|.:|:...:|..|.:...:..|:...|....     |:.
Frog   113 FAEAMDCFLQYVYTGRVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQHFADT 177

  Fly   137 HS------PPRSLAESYAQDLILQHQQQQQQGPA 164
            ||      ..:|.|:...:| ::||::..:.|.|
Frog   178 HSLKTLFTKCKSFAQQAFED-VVQHEEFLELGKA 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	26/97 (27%)
		BTB	32..121	CDD:197585	24/89 (27%)
		HTH_psq	587..622	CDD:283007
klhl24	NP_001072337.1	BTB_POZ_KLHL24_KRIP6	48..168	CDD:349562	29/119 (24%)
		PHA03098	59..566	CDD:222983	37/153 (24%)
		KELCH repeat	354..393	CDD:276965
		KELCH repeat	397..441	CDD:276965
		KELCH repeat	444..489	CDD:276965
		KELCH repeat	492..529	CDD:276965
		KELCH repeat	536..578	CDD:276965
		Kelch	545..591	CDD:128874
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910