DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and Zbtb43

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001342539.1	Gene:	Zbtb43 / 71834	MGIID:	1919084	Length:	504	Species:	Mus musculus

Alignment Length:	426	Identity:	82/426 - (19%)
Similarity:	142/426 - (33%)	Gaps:	152/426 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFF--DAVLSNYASERDPIIIMKDVT 77
            |.:....:|...:|..|||::..:|.:.:||:.||.|.|.:|  ..:|.|  |.|   |::.||.
Mouse    54 STILQKLNQQRQQGQLCDVSIVVQGHIFQAHKAVLAASSPYFCDQVLLKN--SRR---IVLPDVM 113

  Fly    78 FAEV-KCLIEFMYKGEINVEHSSLPSLLKTADDLK----IKGLAEVTWRDDEDGPPPPMA----- 132
            ...| :.::.|.|.|.:.:....:.|.|..|..|:    :....||.     :|.|..:.
Mouse   114 NPRVFENILLFSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVL-----EGNPTVLCQKLNH 173

  Fly   133 AAEFHSPPRS----LAESY------------AQDLILQHQQQQQQGPAAPPLNLHSSAALLERDR 181
            .::..||..|    |.||:            ||:|                           ||.
Mouse   174 GSDHQSPSSSNYNGLVESFELGSGGHTDFPKAQEL---------------------------RDG 211

  Fly   182 ERERERDRERLSPGMEGVLGRMPVMTPLTGASGSAGVGSVSGGTSLEGVAPVEHFLGPKRKRGRP 246
            |.|.|..::.||                         ..|:....|...:..||
Mouse   212 ENEEESTKDELS-------------------------SQVTEHEYLPSNSSTEH----------- 240

  Fly   247 PLDDAYDVFNVRKLAQYAANLEPAQRAYLETARHFT----EEPPLAAHAASMASPPAACPPKQRQ 307
                       .:|:...|:.:..:.....|..|:|    .:|.:.||...:...|        :
Mouse   241 -----------DRLSTEMASQDGEEGTNDSTEFHYTRPLYSKPSIMAHRRWIHVKP--------E 286

  Fly   308 RLR--------HQQQQQQQLLQSESSDQEQPAAGQDWSNLEPNGS------ATPKLLSDGDANKQ 358
            ||.        |....:.|:.:|.::.|...:|       :|:|:      ...|:..:.|   :
Mouse   287 RLEQAWDGMDVHAAYDEHQVTESVNTMQTDHSA-------QPSGAEEEFQIVEKKVEVEFD---E 341

  Fly   359 ETEGG--DESLPAVLTTASSSGTKKL--EKIGERRE 390
            :.||.  ||.:....::......:||  ..||.::|
Mouse   342 QAEGSSYDEQVDFYGSSMEEFSGEKLGGNLIGHKQE 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	28/103 (27%)
		BTB	32..121	CDD:197585	27/95 (28%)
		HTH_psq	587..622	CDD:283007
Zbtb43	NP_001342539.1	BTB	60..160	CDD:306997	29/104 (28%)
		C2H2 Zn finger	413..431	CDD:275368
		C2H2 Zn finger	439..459	CDD:275368
		zf-H2C2_2	451..474	CDD:316026
		C2H2 Zn finger	467..484	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910