DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3726 and klhl40

DIOPT Version :9

Sequence 1:NP_001284917.1 Gene:CG3726 / 31525 FlyBaseID:FBgn0029824 Length:682 Species:Drosophila melanogaster
Sequence 2:NP_001015817.1 Gene:klhl40 / 548534 XenbaseID:XB-GENE-968841 Length:614 Species:Xenopus tropicalis


Alignment Length:285 Identity:61/285 - (21%)
Similarity:108/285 - (37%) Gaps:64/285 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LPQQYC--LRWKYHHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAV-LSNY 63
            ||.|..  || .|..:.||.....:||...|.|..|..:|:....||:||.|||.:|.|: |||.
 Frog     3 LPTQQADELR-LYQQTLLQDGLKDMLDHDNFIDCVLKIQGKEFPCHRLVLAACSPYFRAMFLSNL 66

  Fly    64 ASERDPIIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAE--VTWRDDE-- 124
            ...:...|.::||....:..::.::|..||.:...::..:...|:..:|..:..  |::...:  
 Frog    67 EEGKKKEIDLEDVDPDVMGKILHYIYTSEIEITEKNVQDIFSVANMFQIPSIFTVCVSFLQKKLC 131

  Fly   125 --------------DGPPPPMAAAE-----FH-----------SPPRSLAESYAQDLILQHQQQ- 158
                          |.|...::|.:     ||           ||...:|...:..|.::.::: 
 Frog   132 LSNCLAIFRLGLLLDCPRLAVSARDFVCDRFHLIARDEEFYDLSPDELIAVISSDSLNIEKEEEV 196

  Fly   159 ------------QQQGPAAPPLNLHSSAALLERDRERER-------ERDRERL------SPGMEG 198
                        :::..|.|.:.......|:.:|..:.:       :.|:|.|      ....||
 Frog   197 FEVVLKWALKEKEKRAKALPIIFESIRFRLIPQDYIKNKVEKHELVKSDKELLKKLQMVKDAQEG 261

  Fly   199 VLGRMPVMTPLTGASGSAGVGSVSG 223
            .|......||...:.|..|.|.|:|
 Frog   262 KLPAAVKKTPSKASEGKDGEGVVNG 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3726NP_001284917.1 BTB 21..118 CDD:279045 26/99 (26%)
BTB 32..121 CDD:197585 24/91 (26%)
HTH_psq 587..622 CDD:283007
klhl40NP_001015817.1 BTB_POZ_KLHL40_KBTBD5 6..139 CDD:349649 33/133 (25%)
PHA03098 47..544 CDD:222983 47/240 (20%)
KELCH repeat 344..391 CDD:276965
Kelch 1 353..405
KELCH repeat 395..441 CDD:276965
Kelch 2 406..455
KELCH repeat 446..489 CDD:276965
Kelch 3 456..503
KELCH repeat 493..537 CDD:276965
Kelch 4 505..550
Kelch_1 540..587 CDD:366584
KELCH repeat 540..587 CDD:276965
Kelch 5 552..606
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.