DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and AgaP_AGAP002297

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_565508.1	Gene:	AgaP_AGAP002297 / 3290595	VectorBaseID:	AGAP002297	Length:	331	Species:	Anopheles gambiae

Alignment Length:	318	Identity:	64/318 - (20%)
Similarity:	124/318 - (38%)	Gaps:	65/318 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 DVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPIIIMKDVTFAEVKCLIEFMYKGEINVE 96
            |||:.||.:.:|||::||...|.||.::. |......|::::.:|.:.::..|::|:|.||::||
Mosquito    36 DVTICCESRKLRAHKLVLVLGSPFFRSIF-NEVPTPHPVVMIYNVKYEDLDALVKFLYTGELSVE 99

  Fly    97 HSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPMAAAEFHSPPRSLAESYAQDLILQHQQQQQQ 161
            ...|||||:.|..|::...:.:.        |......:.:....|...::....:|..:..|..
Mosquito   100 RERLPSLLEAARYLQLDEFSTLL--------PYLQETGDLNENLLSAVNAFNSMSLLMDRTNQTN 156

  Fly   162 GPAA------------PPLNLHSSAALLERDRERERERDRERLSPGMEGVLGRMPVMTPLTGASG 214
            ..|.            || ...:||::|..:.|...::.:::|.             :|:.|...
Mosquito   157 DSATIMSTICMLTTNDPP-QPSTSASVLPYNGEAGEQQQQQQLE-------------SPINGEYL 207

  Fly   215 SAGVGSVSGGTSLEGVAPVE-----HFLGPKRKRGRP-------------PLDDAYDVFNVRKLA 261
            .....|:....|.:..:|.|     |::........|             |:|   .:.:.:..|
Mosquito   208 GDDETSMISQDSADSFSPTEVMIMPHYIDKALVSMVPRSVENAIVALFAVPID---PLISQQSAA 269

  Fly   262 QYAANLEP-----AQRAYLETARHFTEEPPLAAHAASMA----SPPAACPPKQRQRLR 310
            .:||...|     .:|...:.....::.||....|...:    :|.....|:|:...|
Mosquito   270 AFAAQNTPNAGTVDERVNDDVYLVLSDSPPAVRSARESSEFIDAPELQYDPRQQDLSR 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	30/85 (35%)
		BTB	32..121	CDD:197585	30/88 (34%)
		HTH_psq	587..622	CDD:283007
AgaP_AGAP002297	XP_565508.1	BTB	25..116	CDD:279045	30/80 (38%)
AgaP_AGAP002297	XP_565508.1	BTB	36..117	CDD:197585	30/81 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920