DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and AgaP_AGAP005745

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_556396.3	Gene:	AgaP_AGAP005745 / 3290035	VectorBaseID:	AGAP005745	Length:	579	Species:	Anopheles gambiae

Alignment Length:	435	Identity:	75/435 - (17%)
Similarity:	151/435 - (34%)	Gaps:	165/435 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 CDVTLACEGQLIRAHRVVLC----------------------ACST-----FFDAVLS----NYA 64
            |:..:.|   ::.|||:||.                      .|::     ||.::|.    |..
Mosquito     5 CNDGVTC---VMPAHRMVLANFSEVSQLRASSAHKTPQINPPQCTSIVRQQFFSSILGALKPNTN 66

  Fly    65 SERDPIIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPP 129
            .....:::..|::...::.|::|||.|:::|....:...|:....|:::|:    |.::::|
Mosquito    67 GSPLTVLLQPDISQPVMQLLLQFMYTGKVSVTQELIGDFLRCGHVLRVRGV----WSEEKEG--- 124

  Fly   130 PMAAAEFHSPPRSLAESYAQDLILQHQQQQQQGPAAPPLNLHSSAALLERDRERERERDRERLSP 194
               :::...|.|::              ..::.||:     ||.:.....|     |.||..::.
Mosquito   125 ---SSDVERPVRTV--------------PSKRQPAS-----HSDSEGSAAD-----EFDRSTVTS 162

  Fly   195 GMEGVLGRMPVMTPLTGASGSAGVGSVSGGT----SLEGVAPVEHFLGPKRKRGRPPLDDAYDVF 255
                       :...:.||.::...|||..|    ..:.:.|.|.   |.:||....|      .
Mosquito   163 -----------VPQASTASNASEPKSVSSSTQEFSDADTLTPHER---PTQKRRNRKL------I 207

  Fly   256 NVRKLAQYAANLEPAQRAYLETARHFTEEPPLAAHAASMASPPAACPPKQRQRLRHQQQQQQQLL 320
            .:.|..:|:::.|             .:|..::::...                        .||
Mosquito   208 KIIKRMRYSSDDE-------------LDEVEVSSNVGF------------------------DLL 235

  Fly   321 QSESSDQEQPAAGQDWSNLEPNGSATPKLLSDGDANKQETEGGDESLPAVLTTASSSGTKKLEKI 385
            :|:|..:|.....:....||..|.|         .:|:|||.|                    |.
Mosquito   236 RSDSETEEGDRVAKRDKELEGKGVA---------EDKEETEDG--------------------KS 271

  Fly   386 GERRERHGKLRHARRLYEKSGEDEVDPPKEEPDELPQPVEEIENE 430
            .:.|:.:..       |:...|||.|..:::.|:..|..|:.::|
Mosquito   272 IDDRDTYDD-------YDDDEEDEDDDDEDDEDDDSQRTEDEKDE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	22/117 (19%)
		BTB	32..121	CDD:197585	21/119 (18%)
		HTH_psq	587..622	CDD:283007
AgaP_AGAP005745	XP_556396.3	BTB	9..118	CDD:295341	21/115 (18%)
AgaP_AGAP005745	XP_556396.3	BTB	14..117	CDD:197585	19/102 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010